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Flashcards in 54-Breakdown of Homeostasis Deck (66)
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61

What are the 2 ways to initiate apoptosis

Mitochondrial/intrinsic
Death receptor/extrinsic

62

nonmorphologic characteristics of necrosis

Pathologic, no gene transcription, unregulated, no energy, lysosome disruption, cell membrane leakage

63

Non morphologic characteristics of apoptosis

Physiologic and non physiologic
Gene transcription
Highly regulated
Needs energy
Cleave chromatic
Lysosome intact
cell membrane intact

64

Morphologic characteristics of necrosis

Death of groups
karyolysis and karyorrhexis
organelles destroyed
Swelling
Inflammatory response

65

Morphologic characteristics of apoptosis

Death in individual cells
Chromatic clumping
Organelles preserved
Cell shrinkage
No inflammation

66

Biochemical pathway that can be manipulated by pharmacology

Apoptosis-cancer