5.8 - HIV Flashcards
The structure of HIV The stages of HIV replication How HIV causes the symptoms of AIDS (18 cards)
What type of virus is HIV?
What’s it’s full name?
Human immunodeficiency virus
What does HIV weaken?
The immune system
What are the components of HIV?
5 components
- Genetic material - Two single strands of RNA.
- Enzymes - One of these enzymes is reverse transcriptase, which allows the virus to convert RNA into DNA.
- Capsid - A layer of protein molecules that surrounds and protects the genetic material.
- Envelope - An outer layer made up of phospholipids.
- Glycoproteins - Also known as attachment proteins or envelope proteins, these help the virus to bind to host cells.
What is the genetic material of HIV?
Two single strands of RNA
What enzyme does HIV contain?
Reverse transcriptase
What is the function of reverse transcriptase?
Converts RNA into DNA
What is the capsid of HIV?
Protein layer protecting genetic material
What is the envelope of HIV?
Outer layer made of phospholipids
What are glycoproteins on HIV?
Attachment proteins that help bind to host cells
What type of cells does HIV use as host cells?
Helper T cells
What happens during HIV replication?
7 stages
- Attachment proteins on the HIV attach to receptors on a helper T cell.
- HIV releases its RNA into the helper T cell.
- Reverse transcriptase converts this RNA into DNA.
- The viral DNA is inserted into the helper T cell’s genome.
- The helper T cell’s DNA is translated to make viral proteins.
- The proteins are used to assemble new HIV particles.
- Fully assembled HIV particles leave the cell in order to infect other cells.
What are the stages of HIV infection?
Stage 1 - Transmission
Stage 2 - Acute infection
Stage 3 - Latency period
Stage 4 - AIDS Development
How is HIV transmitted?
Direct contact with bodily fluids
What happens during acute infection?
Rapid HIV replication
What happens during the latency period?
Low HIV replication
What happens during AIDS development?
HIV reactivates and destroys helper T cells
What is the treatment for HIV/AIDS?
Antiretroviral therapy (ART)
What does ART do?
Reduces viral replication