Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Zak, MSK 2 > Pathology - Skeletal Muscle/NMJ > Flashcards

Pathology - Skeletal Muscle/NMJ Flashcards

1
Q

Sx’s: b/l proximal m. weakness and heliotrope rash

A

Dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the Tx for Myasthenia Gravis

A

AchE antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does BMD differ from DMD

A

Mutated dystrophin gene instead of deleted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Myasthenia Gravis is assc w/…

A

Thymic hyperplasia Thymoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the Tx for Lambert-Eaton Syndrome

A

Resection of cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hist: Endomysial inflammation (CD8) w/ necrotic m. fibers

A

Polymyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Def: inflammatory disorder of skin and SkM

A

Dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Sx’s: Weakness that worsens w/ use and improves w/ rest and includes the eyelids

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lambert-Eaton Syndrome is assc w/…

A

SCLS (paraneoplastic syndrome)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What differentiates Dermatomyositis from Polymyositis clinically

A

No skin involvement in Polymyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is assc w/ Dermatomyositis

A

Carcinoma (Gastric)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sx’s: proximal m. weakness by 1 yo that progresses to distal weakness

A

Duchenne Muscular Dystrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What labs will be significant in Dermatomyositis

A

Increased CrK + ANA and anti-Jo-1 Ab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Def: AutoAbs against postsynaptic AchR at NMJ

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sx’s: Weakness that worsens w/ use and improves w/ rest and spares the eyes

A

Lambert-Eaton Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hist: Perimysial inflammation (CD4) w/ perifascicular atrophy

A

Dermatomyositis

17
Q

What is a heliotrope rash

A

Rash of upper eyelids in Dermatomyositis

18
Q

What is the MC cause of death in DMD

A

Cardiac/Respiratory failure

19
Q

Def: Inflammatory disorder of SkM

A

Polymyositis

20
Q

Def: Abs against presynaptic Ca channels of NMJ

A

Lambert-Eaton Syndrome

Zak, MSK 2 (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions