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Zak, MSK 2 > SkM Relaxant Pharmacology > Flashcards

SkM Relaxant Pharmacology Flashcards

1
Q

Which drugs are NDNM blocking drugs (Isoquinolines)

A 
Atracurim
Cisatracurium
Doxacurium
Mivacurium
Metocurine
Tubocurarine
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2
Q

Which drugs are NDNM blocking drugs (Steroids)

A

Pancuronium
Pipercuronium
Rocuronium
Vecuronium

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3
Q

Which drugs are charged AchEi’s

A 
Ambenonium
Echothiphate
Edrophonium
Neostigmine
Pyridostigmine
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4
Q

Which drugs are uncharged AchEi’s

A 
Donepezil
Galantamine
Physostigmine
Rivastigmine
Tacrine
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5
Q

Which drug is the DNM blocking drug

A

Succinylcholine

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6
Q

MOA: Atropine

A

mAchR antagonist/inhibitor –> decreased PNS activity

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7
Q

MOA: Pralidoxime

A

AchE regenerator –> decreased PNS activity

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8
Q

Which drugs are centrally acting spasmolytics

A 
Baclofen
Carisprodol
Cyclobenazprine
Diazepam
Tizanidine
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9
Q

Which drugs are non-centrally acting spasmolytics

A

Dantrolene

Botulinum toxin

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10
Q

Which drugs are used to Tx MS

A

Glatiramer acetate
IFN-ß-1a/b
Mitoxantrone

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11
Q

Major SE’s: Atracurium

A

Less histamine release

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12
Q

Major SE’s: Cisatracurium

A

Safe w/ renal/hepatic impairment

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13
Q

Major SE’s: Doxacurium

A

Not used in pts w/ renal failure

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14
Q

Major SE’s: Mivacurium

A

Histamin release, CV effects

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15
Q

Major SE’s: Succinylcholine

A

Combo w/ volatile anesthetics –> Malignant hyperthermia

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16
Q

Major SE’s: Ambenonium

A

Causes decreased activity of NDNM blocking agents

Enhances bradycardia of ß-blockers

17
Q

Why is the Echothiphate different from the other drugs in its class

A

Only AchEi requiring Pralidoxime for reversal of its effects

18
Q

Which centrally acting spasmolytic also has anti-anxiety effects

A

Carisprodol

19
Q

Which non-centrally acting spasmolytic can cause hepatitis

A

Dantrolene

20
Q

Which centrally acting spasmolytics are schedule IV substances

A

Carisprodol

Diazepam

Zak, MSK 2 (17 decks)

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