Thurs Wk 5 Mixed 2 Flashcards
atrophy in Alzeheimer Disease occurs in __ lobe and hippocampus (esp early)
think lung abscess w __
key player is __ as they release cytotoxic granules
this kills bacteria, but also leads to __ necrosis
__ is deficiency in NER necessary for correcting UV light exposure
skin of infant is __ initially, but leads to atropy, telangectasias, altered pigmentation and __
NER- UV exposure leads to __, which is recognized and cut on both sides
DNA poly synthesizes fragment and __ seals gap
__ is AR cx of mutation in genes responding to DNA crosslinks
see A__ and short stature, hypoplastic thumbs, and malignancy
temporoparietal
air fluid level
PMN
liquefactive
XP normal cancer thymine dimer DNA ligase
fanconi anemia
aplastic anemia
fructose abosrbed in SI by _
F1P is converted by __ to DHAP and glyceraldehyde
G becomes G3p via triose _ and both go through glycolysis
pt w chronic COPD on supplemental O2 reduces __ chemoreceptor stimulation w dec RR
Central chemoreceptors are in __ and respond to low pH and high CO2
peripheral chemoreceptors are __/__ bodies that can sense low O2 as well as O2/H
pulmonary stretch receptors are myelinated/unmyelinated __ fibers
regulate __ of inspiration depending on lung distension
thus CO2 is main __ of respiration in healthy indiv
GH/EPO/cytokines use __ receptors
TSH, glucagon, PTH use __ GPCR
GLUT5
Aldolase B
kinase
peripheral medulla carotid/aortic C depth driver
JAK-STAT
Gs
perform __ analysis to identify why AE occurred
A__ is p450 enzyme in ovarian tissue, AC, subq, breast
can use aromatase inhibs E, L, A to prevent conversion of androgens to estrogen for ER pos tumors in POSTMEN woman
use continuous __ in premen woman
interscalene nerve block used for anesthesia to /
admin in __ triangle and can paralyze the diaphragm
__ roots of BP
3 trunks: S, M, I
3 anterior/posterior __
3 __
fatty foods inc _ release resulting in pain w obstruction
released by __ cells to stimulate GB contraction, panc enzymes, and dec gastric emptying
root cause
aromatase
exemestane, letrozole, anastrazole
GnRH
shoulder/upper arm scalene 5 superior, middle, inferior divisions cords
CCK
I cells of D/J
Too rapid correction of hypoNa is __
see quadriplegia due to __ of CS tracts and pseudobulbar palsy of CN 9/10/11
nuclei of CN remain __
too rapid correction of HYPERNATREMIA leads to __
caudate atrophy leads to dilation of __ w reactive gliosis/neuron loss
HD chromosome number _
external ear innervation is great __ nerve, lesser occipital nerve and A_ nerve
majority of ear canal is __ innervation
except posterior portion which is __
Klebsiella is gram neg w thick __ that exhibits mucoid growth
see __ sputum and liquefactive necrosis
normally inhabits _
central pontine myelinosis
demyelination
intact
cerebral edema
lateral ventricles
4
auricular, auricoltemporal
CN V3
vagus nerve
capsule
currant jelly
oropharynx
hypoCa lead to neuromuscular __
metastatic cancer is more likely to cause __
4-12hrs after MI, early \_\_ necrosis w edema/wavy fibers and eosinophilis present 12-24hrs- contraction _ occurs 1-5 days, \_\_ infiltrate 5-10 days, \_\_ phagocytosis of dead cells 10-14 days, \_\_ tissue develops >2w, \_\_ deposited
LV myocardial perfusion occurs in __ due to high systolic IV pressure
thus, duration of __ is limiting factor for blood supply to the myocardium
N/V, confusion, dizziness, tinnitus, fever, tachypnea indicate __ overdose
__ occurs first as MEDULLARY resp center inc ventilation
__ occurs around 12hrs as organic acids accumulate
thus see normal __ and low CO2/HCO3
hyperexcitability
hypercalcemia
coag necrosis PMN macros granulation collagen
diastole
diastole
aspirin
RESP ALKALOSIS
AGAP MA
pH
Factor _ of extrinsic pathway has shortest half life of all coag factors
severe cirrhosis also leads to __ as splanchinc vasodilation/AV shunts form
during inflammation, secretion of __/__ upregulates COX2 prodxn
hepatic hydoxylation of phenytoin is __ thus can be saturated
affected by __ enzymes
OMEPRAZOLE __ p450
Sternocleidomastoid attaches to //_ bones
pulls medial segment __ and posteriorly
Pec major/arm pull lateral clavicle /
ACEI causes __kalemia
7
High output cardiac failure
IL1/TNFa
dose dependent
p450
inhibits
sternum, clavicle, mastoid
superior
inferior/anterior
HYPER
chronic rejection occurs after __ months
due to graft __ damage by cellular/humoral responses against alloantigens
see fibrous __ thickening and tubular atrophy/fibrosis
arterial fibrinoid necrosis/mottling and cyanosis indicate __ reject
__ is comp of prematurity before 32w
dec conciousness, hypotonia, bulging __ and hypoTN, ___ posture, irregular resp
due to rupture of __ near ventricles from which neurons/glial fibers originate
other comps of prematurity inclde RDS, PDA, __ dysplasia, N__ and retinopathy
G/E are main insulin opposing hormones to inc glycogenolysis/gluco
C/G alter trxn of genes to conserve glucose
3
endothelial
intimal
hyperacute
IVH AF decerebrate germinal matrix bronchopulmonary necrotizing enterocolitis
glucagon, epinephrine
cortisol, GH
anti EGFR antibodies C, P
check pt prior to admin to determine _ status
w anesthetic induction, PP of drug rises in blood until it reaches __
speed of saturation depends on __ as highly soluble anesthetics need higher doses to become saturated
blood solubility is __ coefficient
higher blood solubility means __ BGPC
thus, more drug is needed to reach __
ex, NO has low __ and thus saturates brain very quickly
high solubility is absorbed by __ and delays CNS saturation
Low solubility in blood has __ onset and equilibration
cetuximab, panitumumab
KRAS
inhaled gas solubility BGP higher saturation BGPC blood
rapid
transmural fibrinoid necrosis w neg anca is __
leads to __ of involved organs
integrins bind to ECM via C/F/L
also interacts w K/A on intracellular domain
Fibronectins produced by F_ to bind collagen and GAG for cell adhesion/migration
crypto may cause lung sx, dx w __ stain
pt w bacterial meningitis, low platelets, petechial rash has __ sepsis
results in hypoNa, hyperkalemia and hypoglycemia w __ crisis/bilateral infarct
this is __ syndrome
usually due to __ infection
PAN
ischemia
collagen, fibronectin, laminin
keratin, actin
fibroblasts
mucicarmine
DIC
adrenal
Waterhouse Friederichsen
N men
