7-SYSTEMIC FUNGI

Question 1

MOT:

Answer 1

inhalation of spores (mold)

Question 2

Specimen:

Answer 2

Sputum

Question 3

contains HEPA filter

Answer 3

BSL III=BSC class II

Question 4

No

Answer 4

person-to-person contact

Question 5

Colonies:

Answer 5

cottony white to brown

Question 6

blastomycosis/Gilchrist disease

Answer 6

Blastomyces dermatitidis

Question 7

chronic granulomatous and suppurative infection of the lungs, skin and mucous membranes

Answer 7

Blastomyces dermatitidis

Question 8

Primary Lung

Answer 8

Blastomyces dermatitidis

Question 9

Chronic skin-bone

Answer 9

Blastomyces dermatitidis

Question 10

Slow to moderate growers

Answer 10

Blastomyces dermatitidis

Question 11

Rapid growers (3 to 4 days)

Answer 11

Blastomyces dermatitidis

Question 12

Dipmorphic

Answer 12

Coccidioides immitis

Question 13

habitat: soil

Answer 13

Coccidioides immitis

Paracoccidioides brasiliensis

Question 14

habitat: alkaline soil

Answer 14

Histoplasma capsulatum

Question 15

coccidioidomycosis/Valley fever

Answer 15

Coccidioides immitis

Question 16

Asymptomatic pulmonary disease

Answer 16

Coccidioides immitis

Question 17

skin infections are characterized by erythema nodosum and multiforme and arthritis

Answer 17

Coccidioides immitis

Question 18

Symptomatic: fever, respiratory distress, cough, anorexia, headache, malaise, and myalgias

Answer 18

Coccidioides immitis

Question 19

most virulent human mycosis

Answer 19

Coccidioides immitis

Question 20

histoplasmosis

Answer 20

Histoplasma capsulatum

Question 21

coin lesions, flattened lesions in lungs

Answer 21

Histoplasma capsulatum

Question 22

very fatal and may lead to death to immunodeficient/ immunosuppressed patient

Answer 22

Histoplasma capsulatum

Question 23

Acquired in bird poops, bat guanos/ bat poops

Answer 23

Histoplasma capsulatum

Question 24

“Cave’s disease”

Answer 24

Histoplasma capsulatum

Question 25

Specimen: blood, urine, CSF

Answer 25

Histoplasma capsulatum

Question 26

Paracoccidiodomycosis

Answer 26

Paracoccidioides brasiliensis

Question 27

South American blastomycosis

Answer 27

Paracoccidioides brasiliensis

Question 28

Brazilian blastomycosis

Answer 28

Paracoccidioides brasiliensis

Question 29

Lutz-Splendore-Almeida disease

Answer 29

Paracoccidioides brasiliensis

Question 30

paracoccidioidal granuloma

Answer 30

Paracoccidioides brasiliensis

Question 31

lung infection

Answer 31

Paracoccidioides brasiliensis

Question 32

asymptomatic and self- limiting

Answer 32

Paracoccidioides brasiliensis

Question 33

spelunker’s disease

Answer 33

Histoplasma capsulatum

Question 34

Darling’s disease (pulmonary disease)

Answer 34

Histoplasma capsulatum

Question 35

cave disease

Answer 35

Histoplasma capsulatum

Question 36

reticuloendothelial cytomycosis

Answer 36

Histoplasma capsulatum

Question 37

not common

Answer 37

Paracoccidioides brasiliensis

Question 38

Endemic in Mississippi and Ohio river valleys

Answer 38

Blastomyces dermatitidis

Question 39

Endemic in Southwest United States (Mexico), Central and South America

Answer 39

Coccidioides immitis

Question 40

Endemic in Ohio, Missouri, Mississippi river valleys

Answer 40

Histoplasma capsulatum

Question 41

Endemic in Central and South America

Answer 41

Paracoccidioides brasiliensis

Question 42

Culture Media: Blood agar

Answer 42

Blastomyces dermatitidis

Question 43

White to dark tan; young colonies tenacious, older colonies glabrous to woolly

Answer 43

Blastomyces dermatitidis

Question 44

Culture: 22oC

Answer 44

Coccidioides immitis

Question 45

White to tan to dark gray

Answer 45

Coccidioides immitis

Question 46

Young colonies tenacious, older colonies cottony

Answer 46

Coccidioides immitis

Question 47

Culture: pines medium, glucose-cysteine blood, or BHI with blood agar

Answer 47

Histoplasma capsulatum

Question 48

White to brownish mold

Answer 48

Histoplasma capsulatum

Question 49

Woolly, cottony, or granular

Answer 49

Histoplasma capsulatum

Question 50

BHI with blood agar- confirmatory test for Histoplasma capsulatum (grow under 37oC)

Answer 50

Histoplasma capsulatum

Question 51

Wright’s-Giemsa for capsule

Answer 51

Histoplasma capsulatum

Question 52

White to beige; colony glabrous, leathery, flat to wrinkled, folded, or velvety

Answer 52

Paracoccidioides brasiliensis

Question 53

Hyphae: fine hyaline septate hyphae

Answer 53

Blastomyces dermatitidis

Question 54

Conidia: lollipop in appearance, borne directly from the hyphae or on conidiophores

Answer 54

Blastomyces dermatitidis

Question 55

Yeast: large yeast (8-12 um) o resembles the figure 8

Answer 55

Blastomyces dermatitidis

Question 56

Daughter cell is attached by broad necks

Answer 56

Blastomyces dermatitidis

Question 57

Hyphae: septate hyaline with varying widths

Answer 57

Coccidioides immitis

Question 58

Conidia: arthroconidia (barrel shaped)

Answer 58

Coccidioides immitis

Question 59

Tissue form: spherules (30-60 um) containing endospore

Answer 59

Coccidioides immitis

Question 60

Hyphae: very fine septate hyaline hyphae

Answer 60

Histoplasma capsulatum

Question 61

Macroconidia: sunflower in bloom; large unicellular, spherical with tuberculate walls

Answer 61

Histoplasma capsulatum

Question 62

Microconidia: borne directly or in short conidiophores

Answer 62

Histoplasma capsulatum

Question 63

Yeast form: blastoconidia with narrow necks

Answer 63

Histoplasma capsulatum

Question 64

Hyphae: same with Coccidiodes

Answer 64

Paracoccidioides brasiliensis

Question 65

Conidia: not common

Answer 65

Paracoccidioides brasiliensis

Question 66

Yeast: mariner’s wheel

Answer 66

Paracoccidioides brasiliensis