RETRO, CALICI, REO, ORTHOYXO, FILO Flashcards

1
Q

Icosahedral, enveloped virion

A

RETROVIRIDAE

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2
Q

80-130 nm

A

RETROVIRIDAE

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3
Q

Contain an RNA-dependent DNA polymerase for replication - Reverse transcription

A

RETROVIRIDAE

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4
Q

Genus: Lentivirus

A

RETROVIRIDAE

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5
Q

2 virus: HIV and HTLV 1 and 2

A
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6
Q

Genera: Norovirus, Sapovirus, Lagovirus, Vesivirus

A

CALICIVIRIDAE

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7
Q

Small, naked virus

A

CALICIVIRIDAE

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8
Q

HUMAN IMMUNODEFICIENCY VIRUS

A

RETROVIRIDAE

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9
Q

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

A

RETROVIRIDAE

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10
Q

NORWALK VIRUS

A

CALICIVIRIDAE

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11
Q

By by Luc Montagnier (1983)

A

HUMAN IMMUNODEFICIENCY VIRUS

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12
Q
  • Simian Virus: acquired from monkeys
A

HUMAN IMMUNODEFICIENCY VIRUS

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13
Q

: causes Acquired Immunodeficiency Syndrome

A

HIV-1

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14
Q

: restricted in West Africa

A

HIV-2

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15
Q

isolated by Robert Gallo in 1981

A

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

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16
Q

: causes adult acute T-cell lymphocytic leukemia, HTLV-I-associated myelopathy/tropical spastic paraparesis

A

HTLV-1

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17
Q

: linked to neurological disease

A

HTLV-2

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18
Q
  • Not associated w/ malignancies
A

HTLV-2

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19
Q

first studied from an epidemic of diarrhea in Norwalk, Ohio

A

NORWALK VIRUS

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20
Q

body fluids
sexual intercourse
parenteral (sharing of needles)
transfusion and organ transplantation
vertical transmission

A

HUMAN IMMUNODEFICIENCY VIRUS

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21
Q

sexual intercourse
parenteral
transfusion

A

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

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22
Q

ingestion
- highly contagious
- gastroenteritis in adults and elderly

A

CALICIVIRIDAE

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23
Q

lymphadenopathy and fever

A
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24
Q

opportunistic infections

A
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25
Q

malignancies

A
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26
Q

wasting

A
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27
Q

AIDS

A
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28
Q

dementia

A
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29
Q
  • Weight loss, malaise
  • Pneumocystis carinii (pneumonia)
  • Herpes, diarrhea
  • Alzheimer’s disease
A

HUMAN IMMUNODEFICIENCY VIRUS

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30
Q
  • Antiretroviral therapy: increases CD4 value of
A

HUMAN IMMUNODEFICIENCY VIRUS

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31
Q

o: normal
o: with HIV

A

400

<200

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32
Q

AIDS was first described on June 5, 1981

A

HUMAN IMMUNODEFICIENCY VIRUS

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33
Q

approx. 38 million infected worldwide (2019) prevalent in Africa

A

HUMAN IMMUNODEFICIENCY VIRUS

34
Q

8500 per day

A

HUMAN IMMUNODEFICIENCY VIRUS

35
Q

1.8M children (vertical transmission)

A

HUMAN IMMUNODEFICIENCY VIRUS

36
Q

Prevalence in 15 - 24 y/o.

A

HUMAN IMMUNODEFICIENCY VIRUS

37
Q

occurrence of rare diseases

A

HUMAN IMMUNODEFICIENCY VIRUS

38
Q

fewer than 200 CD4 lymphocytes per uL of blood

A

HUMAN IMMUNODEFICIENCY VIRUS

39
Q

ELISA (screening), western blot (confirmatory)

A

HUMAN IMMUNODEFICIENCY VIRUS

40
Q

mechanical prophylaxis, not sharing of needles, screening blood

A

HUMAN IMMUNODEFICIENCY VIRUS

41
Q

no vaccines yet

A

HUMAN IMMUNODEFICIENCY VIRUS

42
Q

“cocktail” - Malaria, Hepa B, Hepa C

A

HUMAN IMMUNODEFICIENCY VIRUS

43
Q

good hygiene
water purification
sewage treatment

A

CALICIVIRIDAE

44
Q

Helical, envelop, 75-125 nm

A

ORTHOMYXOVIRIDAE

45
Q

with lipid bilayer envelope with surface glycoproteins (Hemagglutinin (for attachment) and Neuraminidase)

A

ORTHOMYXOVIRIDAE

46
Q

enveloped, helical, single stranded

A

FILOVIRIDAE

47
Q

800-1000 nm

A

FILOVIRIDAE

48
Q

forms long filaments which sometimes curve back upon themselves

A

FILOVIRIDAE

49
Q

EBOLA VIRUS

A

FILOVIRIDAE

50
Q

MARBURG VIRUS

A

FILOVIRIDAE

51
Q

INFLUENZA A, B, AND C

A

ORTHOMYXOVIRIDAE

52
Q

ROTAVIRUS

A

REOVIRIDAE

53
Q

spherical with prominent spikes

A

REOVIRIDAE

54
Q

acquires and loses its envelope during replication

A

REOVIRIDAE

55
Q

Disease: infantile gastroenteritis

A

REOVIRIDAE

56
Q
  • 50% of diarrhea among children
A

REOVIRIDAE

57
Q

Severity: ++++

A

A

58
Q

Severity: ++

A

B

59
Q

Severity: +

A

C

60
Q

Animal Reservoir: Yes

A

A

61
Q

Animal Reservoir: No

A

B, C

62
Q

Antigenic Changes: shift, drift

A

A

63
Q

Antigenic Changes: drift

A

B, C

64
Q

: first reported outbreak came from Congo in 1976 near the Ebola river (highest fatality rate)

A

EBOLA VIRUS

65
Q

: first isolated in Marburg, Germany

A

MARBURG VIRUS

66
Q

fecal-oral, self-limiting

A

REOVIRIDAE

67
Q

droplet spray

A

ORTHOMYXOVIRIDAE

68
Q

pattern shows school children bringing home the disease infecting other family members

A

ORTHOMYXOVIRIDAE

69
Q

Pathogenesis: viruses attack the macrophages and liver cells

A

FILOVIRIDAE

70
Q

internal organs become jelly like in consistency uncontrolled bleeding under the skin

A

FILOVIRIDAE

71
Q

glycoprotein produced by the virus prevents cells to adhere to each other allowing blood to leak out of the blood vessels headache and severe fever

A

FILOVIRIDAE

72
Q

epidemics last for 3 to 6 weeks

A

ORTHOMYXOVIRIDAE

73
Q

90% fatality rate

A

FILOVIRIDAE

74
Q

epidemics stop when there is not enough people to infect

A

FILOVIRIDAE

75
Q

person to person

A

FILOVIRIDAE

76
Q

via contaminated fluid (blood)

A

FILOVIRIDAE

77
Q

Outbreak in Africa

A

FILOVIRIDAE

78
Q

vaccine (for monkeys)

A

FILOVIRIDAE

79
Q

supportive care

A

REOVIRIDAE

80
Q

RotaShield vaccine

A

REOVIRIDAE

81
Q
  • Summer, near drainage
A

REOVIRIDAE