4. Cholinergic Agonists & Antagonists I

Question 1

A 42 year old patient is given a low dose Ach what would you except to happen to the patient?

A. No change
B.increase in blood pressure with bradycardia
C.increase in blood pressure with tachycardia
D.decrease in blood pressure with bradycardia
E. decrease in blood pressure with tachycardia

RFA

Answer 1

Ans. E. low doses of ACh would produce low pressure with reflex tachycardia

A. No change- that would be dumb

B. Increase in blood pressure with bradycardia- would see this in a drug like NE

C. increase in blood pressure with tachycardia- see this in E

D. decrease in blood pressure with bradycardia- see this in high does of ACh.

Question 2

A patient is suffering from post-operative ileus. You choose to prescribe an indirect agonist of acetylcholine. What do you prescribe? (MG)

A. Bethanechol
B. Pilocarpine
C. Galantamine
D. Neostigmine

Answer 2

D. Neostigmine

Question 3

A patient is suffering from post-operative ileus. You choose to prescribe a direct agonist of acetylcholine. What do you prescribe? (MG)

A. Bethanechol
B. Pilocarpine
C. Galantamine
D. Neostigmine

Answer 3

A. Bethanechol

Question 4

A 42 t year old man come to the clinic with dry mouth after investigation it is determined that he has Sjogren Syndrome. What is the drug of choice to treat his dry mouth.

A. Carbachol 
B. Bethanechol 
C. Paratjion 
D. Pilocarpine 
E Neostigmine 

RFA

Answer 4

Ans. Pilocarpine

Question 5

Which of the following drug can be given before aging occurs and acts as a cholinesterase regenerator?

A. Atropine
B. Pralidoxime
C. Physostigmine
D. Pyridostigmine
E. Pilocarpine

SZ

Answer 5

Ans. B. Pralidoxime

Question 6

Which of the following is used to diagnosis myasthenia gravis?

A. Pilocarpine
B. Neostigmine
C. Edrophonium 
D. Pyridostigmine
E. Donepezil 

SZ

Answer 6

Ans. C Edrophonium