I&I) How Viruses Cause Disease Flashcards

1
Q

What is virus made of

What is the journey of a virus

How can virus get into body - pto for prompt

A

Skin, alimentary tract, urogenital, eye

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2
Q

What is apical and basolateral viral release

A

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3
Q

How can virus enter the blood.

What is the presence of virus in blood called

A

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4
Q

Viruses and neural spread

How cab this happen? Pto for promt - what happens here

A

What is neurotropic, neuroinvasivem neurovirulent

GIVE EG

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5
Q

Tissue tropism

What is this. What can determine this. Pto for promt

A

Cell receptors?
Cellular proteins? What can they regulate
Cell protease? - eg?

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6
Q

What makes a virus virulent?

A

—4 points if ya can

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7
Q

How can viruses injure cells? There are THREE ways

A

Cytolyic, non cytolytic, free radicals

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8
Q

Give examples of viruses and what their route of transmission would be

A

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9
Q

What are some types of infectio?

A

For chronic/persisting, what is happening with immune system

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10
Q

Latent infection

What kinds of viruses present with these and how do they work, what happens what do you see

Examples of this

A

What could happen

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11
Q

How does the host response vary between acute and chronic infection

A

—-

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12
Q

How can viruses evade immune system?? Pto for hints, give examples

A

Antigenic variation
Inhibition of antigenic processing
Production of cytokines receptor homologues
Production of immunosuppressive cytokines
Infection of immunocompetant

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13
Q

What can viruses to to inhibit antigen processing? Examples?

How can IL-10 help viruses evade immune system?

What else

A

How are IL-1 and IFN-gamma and IN10 involved too

Examples for all please

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14
Q

What is the structure of influenza virus type a

A

NA - neuroaminidase

HA - hemagglutinin

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15
Q

How can influenza viruses ecade host defence mechanisms? Pto

A

What is the difference between antigenic shift and drift

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