I&I) Drug Allergy

Question 1

What are the two types of drug hypersensitivity reactions and what are their features

Answer 1

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Question 2

How to classify a DHR

Clinical manifestation?

Answer 2

Skin, resp, gut, CVS

Question 3

What is the pathophysiogical princicples of DHR

Answer 3

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Question 4

Immediate DHR: non IgE mediated - how does this happen

What causes this

What symptoms for different drug reactions

Answer 4

ACEi and NSAIDS

Question 5

What happens after mast cell IgE degranulation and during

Answer 5

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Question 6

What drugs most commonly cause adverse drug h R

Answer 6

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Question 7

How could someone atypically present with DHR? How would u manage

Answer 7

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Question 8

How to confirm diagnosis of DHR. When would you do this test.

Answer 8

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Question 9

Beta lac tam allergy

What groups of Abx does this include

Answer 9

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Question 10

Beta lactam allergu — what can you give and alternative

Answer 10

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Question 11

Non-immediate reaction — what is this and what could it entail
What is the time frame of this state

Answer 11

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Question 12

Non immediate drug reaction — what are the clinical manifestations

Answer 12

Delayed and systemic effects

Question 13

How does the standard type IV hypersensitivity reaction present itself

Answer 13

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Question 14

Testing with beta lactam allergy — when would you do this and results

Who would this be done for

Answer 14

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Question 15

When would you not need to do an immunology referral

Answer 15

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Question 16

Local anaesthesia reaction

How does a typical reason present itself

Answer 16

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Question 17

NSAIDs

How does a reaction to this present itself

Answer 17

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