9: HIV and STIs of the GI tract Flashcards Preview

Gastrointestinal Week 5 2016/17 > 9: HIV and STIs of the GI tract > Flashcards

Flashcards in 9: HIV and STIs of the GI tract Deck (29)
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1

How are infections transmitted during sex?

Sexual/genital secretions

Direct innoculation (e.g HSV through skin-skin contact)

Trauma (e.g HCV)

Ingestion (e.g shigella)

Fomites (e.g gonorrhoea, objects)

Injecting drugs (e.g HIV, HCV)

2

Sex under the influence of ___ is becoming more common.

drugs

3

What are some risk factors for developing STIs?

< 25 years old

Different sexual partners

Sex without condoms

MSM

PMX

Deprivation

4

Where in the GI tract can STIs present?

All the way down

5

What is an endoscopy which examines the rectum only?

Proctoscopy

6

20-40% of people with gonorrhea will also have ___.

chlamydia

7

How is an STI like gonorrhoea treated?

Antibiotics

Abstinence

Contacting partners

Education

8

Who needs to be informed following a diagnosis of STI?

Sexual partners

9

Which microorganism causes rectal gonorrhoea?

Neisseria gonorrhoea

10

What transmits Neisseria gonorrhoea?

Direct contact of mucosal surfaces / mucosa-fomite

11

What are the symptoms of rectal gonorrhoea?

Lower abdominal pain

Diarrhoea

Rectal bleeding

Anal discharge

Tenesmus

12

What symptoms may also be associated with rectal gonorrhoea?

Urethral/vaginal discharge

Altered urinary habits

13

What may be seen upon proctoscopy of someone with rectal gonorrhoea?

Inflammation

Pus

14

What is a complication of rectal gonorrhoea if untreated?

Abscesses

15

Which microorganism causes rectal chlamydia?

Chlamydia trachomatis

16

Rectal chlamydia has a similar presentation to gonorrhoea but generally there is less ___.

pus

17

Chlamydia has a similar presentation to gonorrhoea (abdo. pain, rectal bleeding, tenesmus) but tends to be (more / lesssevere with (more / less) pus.

less severe

less pus

18

How is chlamydia treated with drugs?

Azithromycin or doxycycline (better clearance)

19

___ is a multi-system disease.

Syphilis

20

___ is often the cause of multi-system presentations which don't make much sense.

Syphilis

21

Which specific antibiotic is used to treat syphilis?

Benzathene (benzyl)penicillin

22

How does primary syphilis present?

Solitary painless ulcer at site of infection

23

How does secondary syphilis present?

Mucosal ulcers, patchy inflammation - mouth, anogenital, rectal

Condylomata lata - warty lesions in warm, moist regions

Systemic inflammation - nausea, fever, lymphadenopathy

Hepatitis

24

Where does herpes simplex infection occur?

Peri-anal mucosa extending into the rectum

25

What type of drug is used to treat herpes simplex infection?

Antivirals

e.g acyclovir

26

Which infection is now vaccinated against in girls and presents as anal warts?

HPV

27

slide 37 - chlamydia +ve but wouldn't cause fever

LGV - mimics IBD, common in HIV+ men

treatment is doxycycline

28

Which immune-related infection causes loss of GALT tissue?

What complications can this lead to?

HIV

Opportunistic infection

29

Which infection is common in HIV+ men who partake in sex with other men?

Lymphogranuloma venerum (LGV)