GROWTH FACTORS Flashcards

1
Q

what are the GFs involved in ECM deposition and scar formation?

A

TGF-B
platelet derived growth factor
cytokines

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2
Q

name this growth factor?

stimulates production of collage, fibronectin, proteoglycans and inhibits collagen degradation

  • decreases proteinase activity
  • increases activity of TIMPS (tissue inhibitors of metalloproteinases)
A

TGF-B

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3
Q

name this growth factor?

causes migration and proliferation of fibroblasts and smooth muscle cells

A

platelet derived growth factor (PDGF)

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