ABX THERAPY Flashcards

1
Q

sulfonamides

  • sulfamethoxazole
  • sulfisoxazole
  • sulfadiazine

trimethoprine

A

folic acid synthesis and reduction

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2
Q

daptomycin (gram +)

polymyxsin (gram -)

A

membrane integrity

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3
Q

glycopeptides

  • vancomycin
  • bacitracin
A

cell wall synthesis

-peptidoglycan synthesis

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4
Q

penicillinase-sensitive penicillins

penicillinase resistant penicillins

antipseudomonal

cephalosporins

carbapenems

monobactams

A

peptidoglycan cross linking

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5
Q

metronidazole

A

DNA integrity (free radicals)

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6
Q

rifampin

A

mRNA synthesis (rifampin)

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7
Q

fluorquinolones

  • ciprofloxacin
  • levofloxacin

quinolone
-nalidixic acid

A

gyrase

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8
Q
chloramphenicol
clindamycin
linezolid
macrolides
streptogramins
A

protein synthesis

-50s subunit

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9
Q

aminoglycosides
glyclcycline
tetracyline

A

protein synthesis

-30s subunit

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