CANCER THERAPY II Flashcards

1
Q

MTX, 5-FU, 6-MP, Hydroxyurea

inhibits?

A

nucleotide synthesis

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2
Q

alkylating agents, platinum agents, bleomycin, dactinomycin, doxorubicin, etoposide, irinotecan

inhibits?

A

DNA

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3
Q

vinca alkaloids and paclitaxel inhibits?

A

cellular division

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4
Q

thymidine synthesis

A

MTX

5-FU

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5
Q

de novo purine synthesis

A

6-MP

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6
Q

inhibits ribonucleotide reductase

A

hydroxyurea

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7
Q

cross link DNA

A

alkylating agents, platinum agents

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8
Q

DNA stand breakage

A

bleomycin

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9
Q

DNA intercalators

A

dactinomycin, doxorubicin

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10
Q

inhibits topoisomerase II

A

etoposide/teniposide

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11
Q

inhibits topoisomerase I

A

irinotecan/topotecan

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12
Q

inhibit microtubule formation

A

vinca alkaloids

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13
Q

inhibits microtubule disassembly

A

paclitaxel

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14
Q

how does cellular division work again?

A
nucleotide synthesis
DNA
RNA
protein
cellular division
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