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STEP 1 > adrenergic meds > Flashcards

adrenergic meds Flashcards

1
Q

bethanechol

A

activates bowel/bladder smooth muscle; resistant to acetylcholinesterase

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2
Q

pilocarpine

A

contracts ciliary muscle of the eye (open angle glaucoma); contracts pupillary sphincter (closed angle glaucoma); resistant to acetylcholinesterase

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3
Q

dopamine

A

D1=D2>>

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4
Q

scombroid poisoning

A

improperly stored dark-meat fish–> bacterial histidine decarboxylase convertes histidine to histamine (which causes the allergy like symptoms)

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5
Q

donepezil

A

increases ACh

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6
Q

galantamine

A

increases ACh

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7
Q

rivastigmine

A

increases ACh

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8
Q

edrophonium

A

increases ACh

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9
Q

pyridostigmine

A

increases ACh, increases muscle strength; does not penetrate CNS

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10
Q

physostigmine

A

increases ACh, penetrates CNS

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11
Q

neostigmine

A

increases ACh; no CNS penetration

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12
Q

ephedrine

A

indirect general agonist, releases stored catecholamines

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13
Q

cocaine

A

indirect general agonist, reuptake inhibitor

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14
Q

amphetamine

A

indirect general agonist, reuptake inhibitor, releases stored catecholamines

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15
Q

phenoxybenzamine

A

irreversible non-selective alpha blockade

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16
Q

carvedilol

A

non-selective alpha and beta antagonists (so is labetalol)

17
Q

timolol

A

non-selective beta antagonist _1=_2

18
Q

ciguatoxin

A

opens Na+ channels causing depolarization

19
Q

phentolamine

A

reversible non-selective alpha blockade

20
Q

methacholine

A

stimulates muscarinic receptors in airway when inhaled, causes bronchoconstriction

21
Q

tetrodotoxin

A

toxin binds fast voltage-gated Na+ channels in cardiac and nerve tissue preventing depolarization (blocks AP)

22
Q

prazosin

A

_1-selective blocker

23
Q

terazosin

A

_1-selective blocker

24
Q

doxazosin

A

_1-selective blocker

25
Q

tamsulosin

A

_1-selective blocker

26
Q

phenylephrine

A

_1>_2

27
Q

norepinephrine

A

_1>_2>_1

28
Q

mirtazapine

A

_2-selective blocker

29
Q

epinephrine

A

>

30
Q

metoprolol

A

_1 selective antagonist

31
Q

esmolol

A

_1 selective antagonist

32
Q

isoproterenol

A

_1=_2

33
Q

dobutamine

A

_1>_2, _ agonism (constriction/contractility)

34
Q

albuterol

A

_2>_1 agonism

35
Q

salmeterol

A

_2>_1 agonism

STEP 1 (20 decks)

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