adrenergic meds Flashcards Preview

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Flashcards in adrenergic meds Deck (35):
1

bethanechol

activates bowel/bladder smooth muscle; resistant to acetylcholinesterase

2

pilocarpine

contracts ciliary muscle of the eye (open angle glaucoma); contracts pupillary sphincter (closed angle glaucoma); resistant to acetylcholinesterase

3

dopamine

D1=D2>_>_

4

scombroid poisoning

improperly stored dark-meat fish--> bacterial histidine decarboxylase convertes histidine to histamine (which causes the allergy like symptoms)

5

donepezil

increases ACh

6

galantamine

increases ACh

7

rivastigmine

increases ACh

8

edrophonium

increases ACh

9

pyridostigmine

increases ACh, increases muscle strength; does not penetrate CNS

10

physostigmine

increases ACh, penetrates CNS

11

neostigmine

increases ACh; no CNS penetration

12

ephedrine

indirect general agonist, releases stored catecholamines

13

cocaine

indirect general agonist, reuptake inhibitor

14

amphetamine

indirect general agonist, reuptake inhibitor, releases stored catecholamines

15

phenoxybenzamine

irreversible non-selective alpha blockade

16

carvedilol

non-selective alpha and beta antagonists (so is labetalol)

17

timolol

non-selective beta antagonist _1=_2

18

ciguatoxin

opens Na+ channels causing depolarization

19

phentolamine

reversible non-selective alpha blockade

20

methacholine

stimulates muscarinic receptors in airway when inhaled, causes bronchoconstriction

21

tetrodotoxin

toxin binds fast voltage-gated Na+ channels in cardiac and nerve tissue preventing depolarization (blocks AP)

22

prazosin

_1-selective blocker

23

terazosin

_1-selective blocker

24

doxazosin

_1-selective blocker

25

tamsulosin

_1-selective blocker

26

phenylephrine

_1>_2

27

norepinephrine

_1>_2>_1

28

mirtazapine

_2-selective blocker

29

epinephrine

_>_

30

metoprolol

_1 selective antagonist

31

esmolol

_1 selective antagonist

32

isoproterenol

_1=_2

33

dobutamine

_1>_2, _ agonism (constriction/contractility)

34

albuterol

_2>_1 agonism

35

salmeterol

_2>_1 agonism