endo drug sea Flashcards Preview

STEP 1 > endo drug sea > Flashcards

Flashcards in endo drug sea Deck (20):
1

acarbose (alpha-glucosidase inhibitor)

GI disturbances

2

Metformin (biguanide)

GI upset, lactic acidosis (contraindicated in renal failure)

3

canagliflozin (SGLT-2 inhibitor)

glucosuria, UTI, vaginal yeast infections

4

cinacalcet

hypocalcemia

5

glimepiride (2nd gen sulfoylurea)

hypoglycemia

6

glipizide (2nd gen sulfoylurea)

hypoglycemia

7

glyburide (2nd gen sulfoylurea)

hypoglycemia

8

pramlintide (amylin analogs)

hypoglycemia, nausea, diarrhea

9

glucocorticoids

iatrogenic cushings (hypertenision, weight gain, moon facies, buffalo hump, striae, osteoporosis, hyperglycemia, amenorrhea, immunosuppression), steroid diabetes, steroid psychosis

10

chlorpropamide (1st gen sulfonylurea)

increased risk of hypoglycemia in renal failure, disulfiram-like effects

11

tolbutamide (1st gen sulfonylurea)

increased risk of hypoglycemia in renal failure, disulfiram-like effects

12

linagliptin (DPP-4 inhibitor)

mild urinary or respiratory infections

13

saxagliptin (DPP-4 inhibitor)

mild urinary or respiratory infections

14

sitagliptin (DPP-4 inhibitor)

mild urinary or respiratory infections

15

exenatide (GLP-1 analog)

nausea, vomiting, pancreatitis

16

liraglutide (GLP-1 analog)

nausea, vomiting, pancreatitis

17

demeclocycline

nephrogenic DI, photosensitivity, abnormalities of bone and teeth

18

propylthiouracil

skin rash, agranulocytosis (Rare), aplastic anemia, hepatotoxcity

19

methimazole

skin rash, agranulocytosis (Rare), aplastic anemia, possible teratogen (aplasia cutis)

20

pioglitazone, rosiglitazone (glitazones, thiazolidinediones)

weight gain, edema, hepatotoxicity, heart failure, increased risk of fractures