Adrenergic/ Sympathetic Flashcards by rph soon

epinephrine/ adrenaline

DOC for anaphylactic shock
prolongs lidocaine’s duration
inc blood sugar levels

alpha & beta agonist
direct acting adrenergic agonist
sympathetic effect

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norepinephrine

DOC for septic shock
greater vasoconstriction than epi (acts more on a receptors)

alpha & beta agonist
direct acting adrenergic agonist
sympathetic effect

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dopamine

may be used for shocks (never DOC)

low dose: d receptors (0.5 mcg/kg/min)
moderate dose: b receptors (5-15)
high dose: a receptors (>15-20)

alpha & beta agonist
direct acting adrenergic agonist
sympathetic effect

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phenylephrine

use nmt 3 days
watchout for htn px

alpha 1 agonist
direct acting adrenergic agonist
sympathetic effect

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phenylpropanolamine

aka pseudoephedrine
Neozep, Sinutab

alpha 1 agonist
direct acting adrenergic agonist
sympathetic effect

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methoxamine

alpha 1 agonist
direct acting adrenergic agonist
sympathetic effect

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clonidine

oral: px w resistant htn
sublingual: htn crisis

alpha 2 agonist
direct acting adrenergic agonist
parasympathetic effect

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methyldopa

allowed for pregnant
(+) coomb’s test

alpha 2 agonist
direct acting adrenergic agonist
parasympathetic effect

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guanfacine

alpha 2 agonist
direct acting adrenergic agonist
parasympathetic effect

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guanabenz

alpha 2 agonist
direct acting adrenergic agonist
parasympathetic effect

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oxymetazoline

effect on a2 not evident
may still cause rebound congestion

alpha 1&2 agonist
direct acting adrenergic agonist
sympathetic effect

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dobutamine

DOC for cardiogenic shock

beta 1 agonist
direct acting adrenergic agonist
sympathetic effect

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albuterol/salbutamol

short acting beta agonist (SABA)
for asthma
stimulates b1 at high concentration

beta 2 agonist
direct acting adrenergic agonist
sympathetic effect

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terbutaline

short acting beta agonist (SABA)
for asthma
stimulates b1 at high concentration
off label: tocolytic

beta 2 agonist
direct acting adrenergic agonist
sympathetic effect

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metaproterenol

long acting beta agonist (LABA)
for asthma
stimulates b1 at high concentration

beta 2 agonist
direct acting adrenergic agonist
sympathetic effect

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salmeterol

long acting beta agonist (LABA)
for asthma
stimulates b1 at high concentration

beta 2 agonist
direct acting adrenergic agonist
sympathetic effect

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formeterol

long acting beta agonist (LABA)
for asthma
stimulates b1 at high concentration

beta 2 agonist
direct acting adrenergic agonist
sympathetic effect

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isoproterenol

beta 1&2 agonist
direct acting adrenergic agonist
sympathetic effect

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tyramine

from red wine, cheese, beer, chocolate
converted to tyrosine (catecholamines)
can cause htn w MAOI

indirect acting adrenergic agonist
sympathetic effect

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methylphenidate

Study These Flashcards

Ritalin
for ADHD, anorexiant, narcolepsy
inc catecholamines release

indirect acting adrenergic agonist
sympathetic effect

amphetamine

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for ADHD, anorexiant, narcolepsy
inc catecholamines release

indirect acting adrenergic agonist
sympathetic effect

phentermine

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for ADHD, anorexiant, narcolepsy
inc catecholamines release

indirect acting adrenergic agonist
sympathetic effect

ephedrine

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alkaloid
mixed (direct & indirect adrenergic agonist)
sympathetic effect

metaraminol

Study These Flashcards

mixed (direct & indirect adrenergic agonist)
sympathetic effect

zosin

S/E: orthostatic hypotension remedy: adjust first dose to 1/3 or 1/4 of normal dose alpha 1 blocker adrenergic antagonist parasympathetic effect

yohimbine

tx for impotence alpha 2 blocker adrenergic antagonist sympathetic effect

phenoxybenzamine

irreversible & long acting tx for htn due to pheochromocytoma and raynaud disease alpha 1&2 blocker (a2 not evident) adrenergic antagonist parasympathetic effect

phentolamine

reversible, short acting pheochromocytoma induced htn alpha 1&2 blocker (a2 not evident) adrenergic antagonist parasympathetic effect

propranolol

prototype DOC for stage fright CI: asthma masks hypoglycemia symptoms (tachycardia, nervousness, tremor) non selective beta blocker adrenergic antagonist paraysmpathetic effect

nadolol

CI: asthma masks hypoglycemia symptoms (tachycardia, nervousness, tremor) non selective beta blocker adrenergic antagonist paraysmpathetic effect

sotalol

CI: asthma masks hypoglycemia symptoms (tachycardia, nervousness, tremor) non selective beta blocker adrenergic antagonist paraysmpathetic effect

timolol

dec aqueous humor = tx for glaucoma CI: asthma masks hypoglycemia symptoms (tachycardia, nervousness, tremor) non selective beta blocker adrenergic antagonist paraysmpathetic effect

nebivolol

most cardioselective b1 antagonist adrenergic antagonist parasympathetic effect

celiprolol