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MOD 4 - Pharmacology > Respiratory Drugs > Flashcards

Respiratory Drugs Flashcards

1
Q

rescue medications for asthma

A

relievers
fast acting bronchodilators

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2
Q

maintenance medications for asthma

A

controllers
prevent future attacks

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3
Q

terbutaline

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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4
Q

salbutamol/albuterol

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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5
Q

fenoterol

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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6
Q

formoterol

A

rapid acting; long acting DA
B2 agonist
bronchodilator (reliever & controller)
asthma

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7
Q

salmeterol

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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8
Q

bambuterol

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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9
Q

serevent

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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10
Q

atropine

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic
broncho dilator (reliever)
asthma

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11
Q

ipatropium

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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12
Q

tiotropium

A

very selective
slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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13
Q

oxytropium

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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14
Q

theophylline

A

narrow therapeutic index
major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

fatty meal = inc absorption

methylxanthine
bronchodilator (reliever & controller)
asthma

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15
Q

aminophylline

A

major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

methylxanthine
bronchodilator (reliever & controller)
asthma

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16
Q

doxofylline

A

major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

methylxanthine
bronchodilator (reliever & controller)
asthma

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17
Q

cromolyn sodium

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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18
Q

sodium cromoglycerate

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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19
Q

nedocromil

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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20
Q

ketotifen

A

chromones (oral) NOT NSAID
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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21
Q

zileuton

A

5-lipooxygenase enzyme inhibitor
leukotriene antagonist
controller
asthma

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22
Q

montelukast

A

LTD4 receptor inhibitor
leukotriene antagonist
controller
asthma

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23
Q

zafirlukast

A

LTD4 receptor inhibitor
leukotriene antagonist
controller
asthma

24
Q

mainstay tx for bronchial asthme

A

steroids

(-) phospholipase A2 (converts cholesterol to arachidonic acid)

(-) cytokine release by macrophage
asthma

25
Q

budenoside

A

locally acting inhaled steroids
controller
asthma

26
Q

bedomethasone

A

locally acting inhaled steroids
controller
asthma

27
Q

triamcinolone

A

locally acting inhaled steroids
controller
asthma

28
Q

fluticasone

A

locally acting inhaled steroids
controller
asthma

29
Q

flunisolide

A

locally acting inhaled steroids
controller
asthma

30
Q

hydrocortisone

A

systemic parenteral steroids (IV)
controller
status asthmaticus (non responsive to bronchodilators)

31
Q

methylprednisolone

A

systemic parenteral steroids (IV)
controller
status asthmaticus (non responsive to bronchodilators)

32
Q

prednisone

A

systemic oral steroids
controller
asthma

33
Q

prednisolone

A

systemic oral steroids
controller
asthma

34
Q

phenylephrine

A

short acting topical decongestant
oral decongestant

nmt 3-5 days tx
decongestant (a-agonist)
cough & colds preparations

35
Q

naphazoline

A

intermediate acting topical decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

36
Q

tetrahydrolozine

A

intermediate acting topical decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

37
Q

oxymetazoline

A

long acting topical decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

38
Q

xylometazoline

A

long acting topical decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

39
Q

pseudoephedrine

A

oral decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

40
Q

phenylpropanolamine

A

oral decongestant
nmt 3-5 days tx

decongestant (a-agonist)
cough & colds preparations

41
Q

levodropropizine

A

Levopront

antitussive - peripherally acting
cough & colds preparation

42
Q

benzonatate

A

antitussive - peripherally acting
cough & colds preparation

43
Q

dextrometorphan

A

suppress cough center
inc cough treshold

antitussive - centrally acting
cough & colds preparation

44
Q

codeine

A

lolo

suppress cough center
inc cough treshold

antitussive - centrally acting
cough & colds preparation

45
Q

noscapine

A

suppress cough center
inc cough treshold

antitussive - centrally acting
cough & colds preparation

46
Q

butamirate citrate

A

Sinecod
lesser side effect

suppress cough center
inc cough treshold

antitussive - centrally acting
cough & colds preparation

47
Q

guaifenesin

A

aka glyceryl guaiacolate
Robitussin

expectorant (inc respiratory tract fluid = madulas)
cough & colds preparation

48
Q

hypertonic saline

A

decrease viscosity (break disulfide bonds)

mucolytics
cough & colds preparation

49
Q

n-acetylcysteine

A

Fluimucil
decrease viscosity (break disulfide bonds)

mucolytics
cough & colds preparation

50
Q

acetylcysteine

A

Mucomyst

decrease viscosity (break disulfide bonds)

mucolytics
cough & colds preparation

51
Q

ambroxol

A

Mucosolvan
stimulate cilia to expel & tunaw phlegm

mucoregulators
cough & colds preparation

52
Q

carbocisteine

A

Solmux
stimulate cilia to expel & tunaw phlegm

mucoregulators
cough & colds preparation

53
Q

bromhexine

A

Bisolvon
stimulate cilia to expel & tunaw phlegm

mucoregulators
cough & colds preparation

54
Q

chlorphenamine

A

antihistamine
cough & colds preparation

55
Q

diphenyhydramine

A

antihistamine
cough & colds preparation

56
Q

inhaler instructions

A

puff + inhale (forceful)
gargle after = avoid steroids affecting normal flora (candida albicans)

MOD 4 - Pharmacology (19 decks)

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