Autonomics - General Flashcards by rph soon

Q

Sympathetic: eyes

A

pupil dilates (mydriasis)

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Q

Sympathetic: glands

A

thick, viscid secretions

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Q

Sympathetic: lungs

A

bronchodilation

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Q

Sympathetic: heart

A

inc chronotropy (HR)
inc dromotropy (conduction)
inc inotropy (contractility)

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Q

Sympathetic: peripheral BV

A

vasoconstriction
governed by b cells

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Q

Sympathetic: skeletal BV

A

vasodilation
governed by a cells

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Q

Sympathetic: bladder

A

sphincter closes
bladder detrusser relaxes

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Q

Sympathetic: GIT

A

dec motility

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Q

Sympathetic: male genitalia

A

ejaculation

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Q

Sympathetic: uterus

A

relaxation (tocolysis)

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Q

Parasympathetic: eyes

A

pupil constricts (miosis)

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Q

Parasympathetic: glands

A

tears
copious watery saliva

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Q

Parasympathetic: lungs

A

bronchoconstriction
inc secretion

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Q

Parasympathetic: heart

A

dec chorno, dromo, ino

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Q

Parasympathetic: GIT

A

inc motility

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Q

Parasympathetic: bladder

A

sphincter open
bladder detrusser contracts

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Q

Parasympathetic: male genitalia

A

erection

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Q

Parasympathetic: uterus

A

contraction (oxytocic)

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Q

metabotropic

Study These Flashcards

A

may jowang g protein

Q

M1

Study These Flashcards

A

Gq
CNS

Q

M2

Study These Flashcards

A

Gi
heart

Q

M3

Study These Flashcards

A

Gq
GIT/glands/other

Q

M4

Study These Flashcards

A

Gi
CNS

Q

M5

Study These Flashcards

A

Gq
CNS

Alpha 1

Gq (IP3 & diacyl glycerol) bladder, peripheral BV, eyes

Alpha 2

Gi (dec CAMP) peripheral BV, brain

Beta 1

Gs (inc CAMP) heart

Beta 2

Gs (inc CAMP) lungs, skeletal muscles BV, uterus

Beta 3

Gs (inc CAMP) adipose tissue

longer post ganglionic neuron

sympathetic

longer preganglionic neuron

parasympathetic

Sympathetic: signal source

thoracolumar (spine) T1-T12 & L1-L2

Paraympathetic: signal source

brainstem & cranio-sacral

Sypmathetic: Catecholamines

Cholinergic preganglionic neuron (ACh) adrenergic postganglionic neuron (NE)

Paraypmathetic: Catecholamines

Cholinergic pre and postganglionic neuron (ACh)

L-dopa

tyrosine + OH

Dopamine

L-dopa - carboxylic acid

Norepinephrine

dopamine + OH

Epinephrine

noradrenaline + methyl

(-) storage of dopamine

reserpine

(-) release of NE

guanethidine guanadrel bretylium

(-) reuptake of NE

TCA cocaine reboxetine

(-) formation of L-DOPA

metyrosine

(-) storage of ACh

vesamicol

(-) release of ACh

botulinum toxin

(-) reuptake of choline

hemicholinium