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MOD 4 - Pharmacology > Autonomics - General > Flashcards

Autonomics - General Flashcards

1
Q

Sympathetic: eyes

A

pupil dilates (mydriasis)

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2
Q

Sympathetic: glands

A

thick, viscid secretions

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3
Q

Sympathetic: lungs

A

bronchodilation

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4
Q

Sympathetic: heart

A

inc chronotropy (HR)
inc dromotropy (conduction)
inc inotropy (contractility)

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5
Q

Sympathetic: peripheral BV

A

vasoconstriction
governed by b cells

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6
Q

Sympathetic: skeletal BV

A

vasodilation
governed by a cells

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7
Q

Sympathetic: bladder

A

sphincter closes
bladder detrusser relaxes

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8
Q

Sympathetic: GIT

A

dec motility

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9
Q

Sympathetic: male genitalia

A

ejaculation

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10
Q

Sympathetic: uterus

A

relaxation (tocolysis)

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11
Q

Parasympathetic: eyes

A

pupil constricts (miosis)

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12
Q

Parasympathetic: glands

A

tears
copious watery saliva

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13
Q

Parasympathetic: lungs

A

bronchoconstriction
inc secretion

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14
Q

Parasympathetic: heart

A

dec chorno, dromo, ino

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15
Q

Parasympathetic: GIT

A

inc motility

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16
Q

Parasympathetic: bladder

A

sphincter open
bladder detrusser contracts

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17
Q

Parasympathetic: male genitalia

A

erection

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18
Q

Parasympathetic: uterus

A

contraction (oxytocic)

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19
Q

metabotropic

A

may jowang g protein

20
Q

M1

A

Gq
CNS

21
Q

M2

A

Gi
heart

22
Q

M3

A

Gq
GIT/glands/other

23
Q

M4

A

Gi
CNS

24
Q

M5

A

Gq
CNS

25
Q

Alpha 1

A

Gq (IP3 & diacyl glycerol)
bladder, peripheral BV, eyes

26
Q

Alpha 2

A

Gi (dec CAMP)
peripheral BV, brain

27
Q

Beta 1

A

Gs (inc CAMP)
heart

28
Q

Beta 2

A

Gs (inc CAMP)
lungs, skeletal muscles BV, uterus

29
Q

Beta 3

A

Gs (inc CAMP)
adipose tissue

30
Q

longer post ganglionic neuron

A

sympathetic

31
Q

longer preganglionic neuron

A

parasympathetic

32
Q

Sympathetic: signal source

A

thoracolumar (spine)
T1-T12 & L1-L2

33
Q

Paraympathetic: signal source

A

brainstem & cranio-sacral

34
Q

Sypmathetic: Catecholamines

A

Cholinergic preganglionic neuron (ACh)
adrenergic postganglionic neuron (NE)

35
Q

Paraypmathetic: Catecholamines

A

Cholinergic pre and postganglionic neuron (ACh)

36
Q

L-dopa

A

tyrosine + OH

37
Q

Dopamine

A

L-dopa - carboxylic acid

38
Q

Norepinephrine

A

dopamine + OH

39
Q

Epinephrine

A

noradrenaline + methyl

40
Q

(-) storage of dopamine

A

reserpine

41
Q

(-) release of NE

A

guanethidine
guanadrel
bretylium

42
Q

(-) reuptake of NE

A

TCA
cocaine
reboxetine

43
Q

(-) formation of L-DOPA

A

metyrosine

44
Q

(-) storage of ACh

A

vesamicol

45
Q

(-) release of ACh

A

botulinum toxin

46
Q

(-) reuptake of choline

A

hemicholinium

MOD 4 - Pharmacology (19 decks)

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