Agents Used In Anemias And Hematopoetic GF Flashcards Preview

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Flashcards in Agents Used In Anemias And Hematopoetic GF Deck (11)
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SimD of ferrous sulfate with high Fe content

Ferrous fumarate

1

SimD of ferrous sulfate administered through IV

Iron dextran, iron sucrose, sodium ferric gluconate complex

2

Acute SE of Fe/chronic Fe overload

Necrotizing gastroenteritis / hemochromatosis

Antidote: deferoxamine

3

Role of B12 in RBC synth

Cofactor in transfer of 1-carbon unit in DNA synth

* def cause neuro defects, not seen in folate deficiency

4

B12 absorbed in ___

Distal ileum

5

B12 deficiency

Tetrafolate is low

6

Neural tube defect

Folate deficiency

7

Absorption of frolic acid at

Proximal jejunum

8

Hematopoietic GF

Epoetin alpha

Hb level maintained below 12g/dl

9

DOC for neutropenia assoc with chemotx

Filgrastim, sargramostin (G-CSF)

10

Megakaryote GF

Oprelvekin (IL-11)