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Flashcards in Alcoholism Deck (20):
1

Alcohol = ___ kcal/g

7

2

___% of heavy drinkers' daily calories come from alcohol

50

3

Alcoholism may affect ___-___% of patients seen at hospital

30-50

4

___% of cirrhosis cases are due to alcoholism

75

5

Alcohol is associated with _____ deaths annually

250,000

6

50% of certain Asians are deficient in an ____ isoenzyme

ALDH

7

Ethanol -> _____ -> acetate

acetaldehyde

note: NAD+ is electron acceptor

8

What are the metabolic effects of alcoholism?

lactic acidosis, ketosis
hypoglycemia
fatty liver
ketone body formation

9

Acetaldehyde is ____ reactive

glutathione

10

Acetaldehyde can react with ____ and effect membrane proteins

hemoglobin

11

Some of the proteins that can be effected by alcoholism and production of acetaldehyde are contractile proteins found where?

heart

12

Cyt P450 is part of the MEOS system and involved in drug and alcohol elimination. Alcohol may ___ some drug metabolism, while the MEOS system may ___ metabolism of other drugs.

depress; increase

13

1 oz of alcohol (86 proof) = ____ cal

71

14

1 "drink" = ___-___ cal

80-120

15

1 pint (86 proof) = ____ cal

1141

16

1 liter wine (12%) = ____ cal

673

17

There is commonly abnormal nutrient levels in alcoholics. Explain why this can happen.

inadequate food intake
poor meal choices
maldigestion
hyperexcretion of nutrients
nutrient requirements are increased due to alcoholism

18

What are three neurologic consequences of alcoholism?

polyneuropathy; wernike-korsakoff syndrome; dementia - cortical degeneration

19

How is fetal alcohol syndrome avoided?

NO ALCOHOL

20

For the following two scenarios, which one is the result of acute alcohol intake and which one is the result of a chronic alcoholism state?
alcohol may depress some drug metabolism
MEOS system may increase metabolism of other drugs

Acute: alcohol may depress some drug metabolism (due to competition)
Chronic: MEOS system may increase metabolism of other drugs