AMINO ACIDS (LECTURE) Flashcards

(45 cards)

1
Q

Are organic compounds that serve as the BUILDING BLOCKS OF PROTEINS, which are essential for numerous biological processes in the human body.

A

Amino acids

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2
Q

Amino acids consist of (5)

A

Carbon
Hydrogen
Oxygen
Nitrogen
Sulfur

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3
Q

Each amino acid has 3 group that determines its properties
1. (-NH2)
2. (-COOH)
3. (R-group)

A

Amine group
Carboxyl group
Side chain (R-group)

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4
Q

TYPES OF AMINO ACIDS
1. cannot be synthesized by the body; must be obtained from diet (e.g. , leucine, valine, lysine)
2. Synthesized by the body (e.g., glycine, alanine, glutamine)
3. Required in certain conditions like illness or stress (e.g., arginine, cysteine)

A

Essential amino acid
Non-essential amino acid
Conditionally essential amino acid

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5
Q

ROLE OF FUNCTIONS
1. Amino acids combine to form PEPTIDES and PROTEINS which are crucial for muscle growth, tissue repair, enzyme production and immune function

  1. Many enzymes and hormones (e.g., insulin, growth hormone) are made from amino acids
A

Protein synthesis
Enzyme and hormone production

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6
Q

ROLES OF FUNCTIONS
3. when carbohydrates are scarce, amino acids can be metabolized for energy (___)

  1. Amino acids like ___ (precursor to serotonin) and ___ (precursor to dopamine, adrenaline) regulate mood, sleep and stress response
A

Energy source
gluconeogenesis
Neurotransmitter synthesis
Trytophan
TYROSINE

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7
Q

ROLES OF FUNCTION
5. are proteins made from amino acids that fight infections
• ___ nasa loob ng katawan
• ___ the body produce antibodies to fight the disease (added protection)

  1. The proteins that transport oxygen while others carry lipids, vitamins and minerals
  2. Act as buffers, helping regulate blood and cellular pH
A

Antibodies (immunoglobulins)
Passive
Induce
Hemoglobin
Amino acids

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8
Q

ROLES OF FUNCTION
8. Amino acids like CYSTEINE help produce ___, a key antioxidant that removes toxins

  1. COLLAGEN from ___, ___ strengthens skin, tendons, and bones; keratin supports hair and nails
A

Glutathione
Glycine
Proline

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9
Q

SOURCES

CONTAIN ALL ESSENTIAL AMINO ACIDS

Meat
Fish
Eggs
Dairy
Quinoa
Soy

A

Complete proteins

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10
Q

SOURCES

LACK SOME ESSENTIAL AMINO ACIDS

Beans
Nuts
Grains

A

Incomplete proteins

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11
Q

ESSENTIAL AMINO ACIDS
KEY FUNCTIONS

• Needed for growth, tissue repair, neurotransmitter (histamine) production

• Meat, fish, poultry, dairy, grains

A

Histidine

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12
Q

ESSENTIAL AMINO ACIDS

• muscle metabolism, immune function, energy regulation

• Eggs, soy, cheese, fish, meat

A

Isoleucine (BCAA)

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13
Q

ESSENTIAL AMINO ACIDS

• Stimulates muscle protein synthesis, regulates blood and sugar

• Beef, chicken, peanuts, len tils

A

Leucine (BCAA)

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14
Q

ESSENTIAL AMINO ACIDS

• Collagen formation, calcium absorption, antiviral properties

• Fish, eggs, beans, quinoa

A

Lysine

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15
Q

ESSENTIAL AMINO ACIDS

• Antioxidant (precursor to cysteine), detoxification, fat metabolism

• Brazil nuts, eggs, seeds, meat

A

Methionine

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16
Q

ESSENTIAL AMINO ACIDS

• Precursor to dopamine, norepinephrine, tyrosine

• Soy, cheese, nuts, seeds

A

Phenylalanine

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17
Q

ESSENTIAL AMINO ACIDS

• Supports immune system, collagen/elastin production

• Cottage chesse, lentils, fish

A

Threonine

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18
Q

ESSENTIAL AMINO ACIDS

Precursor to dopamine, norepinephrine, tyrosine

• Soy, cheese, nuts,seeds

A

Phenylalanine

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19
Q

ESSENTIAL AMINO ACIDS

• serotonin/melatonin precursor (regulates mood and sleep)

• Turkey, milk, bananas, oats

20
Q

ESSENTIAL AMINO ACIDS
• Muscle repair, energy production, nervous system function

• Mushrooms, grains, dairy, meat

A

Valine (BCAA)

21
Q

NON ESSENTIAL AMINO ACIDS

• Glucose metabolism, immune support

• meat, eggs, fish, dairy
• produce ANTIBODIES of the body

22
Q

NON ESSENTIAL AMINO ACIDS

• nitric oxide production (blood flow) wound healing

• Red meat, nuts, seeds, seafood

23
Q

NON ESSENTIAL AMINO ACIDS

• Nervous system function, ammonia detoxification

• Dairy, beef, poultry, asparagus

24
Q

NON ESSENTIAL AMINO ACIDS

• neurotransmitter, energy production (KREB’S CYCLE)

• Oysters, lentils, soy

A

Aspartic acid

25
NON ESSENTIAL AMINO ACIDS • antioxidant (glutathione synthesis) skin/hair health • Garlic, onions, broccoli, poultry
Cysteine
26
NON ESSENTIAL AMINO ACIDS • Neurotransmitter (learning and memory) • Soy sauce, tomatoes, cheese
Glutamic acid
27
NON ESSENTIAL AMINO ACIDS • gut health, immune support, muscle recovery • Cabbage, spinach, beef
Glutamine
28
NON ESSENTIAL AMINO ACIDS • collagen synthesis, brain function, detox • Bone broth, gelatin, spinach
Glycine
29
NON ESSENTIAL AMINO ACIDS • skin/joint health (collagen components) • Egg whites, cabbage, mushrooms
Proline
30
NON ESSENTIAL AMINO ACIDS • Fat metabolism, antibody production • Soy, nuts, eggs, meat
Serine
31
NON ESSENTIAL AMINO ACIDS • Dopamine/adrenaline precursor (stress and focus) • Cheese, soy, chicken, almonds
Tyrosine
32
Under certain conditions (illness, stress, intense exercise) some non-essential amino acids become essential because the body can't produce enough
Conditional amino acids
33
CONDITIONAL AMINO ACIDS • ____ needed during injury/infection • ____ required if methionine intake is low • ____ Critical for gut healing and immune stress • ____ important during prolonged stress (Ex. If magkaroon ng sudden exam, ito ang nar-release)
Arginine Cysteine Glutamine Tyrosine
34
AMINO ACID STRUCTURE 1. Act as a BASE; can accept proton (H+) 2. Acts as an ACID; can donate a proton (H+) 3. A single hydrogen bonded to the central carbon 4. Varies for each amino acid and determines its UNIQUE PROPERTIES (e.g., polar, nonpolar, acidic, basic)
Amino group Carboxyl group Hydrogen atom R-group (Side chain)
35
A molecule that has a positive and negative charges, but is overall electrically neutral. This is especially important in amino acids, which commonly exist as zwitterions in biological systems
Zwitterion
36
When the pH turns -7.4 the AMINO GROUP (-NH2) ___ a proton and becomes -NH3 (___charge) The ___ group (-COOH) loses a proton and becomes (___) negative charge So the amino acid has both charges, but the net charge is __
Gains Positive Carboxyl -COO Zero
37
Zwitterion explain (See-saw) • One child represents the positive charge (AMINO GROUP) • the other represents the negative charge (CARBOXYL GROUP) • the seesaw is perfectly balanced–this is the zwitterion state
38
ZWITTERION IMPORTANCE • ZWITTERION are ____ in water, which is crucial for amino acids to function in the body • Zwitterion help maintain ___ balance in cells and tissues • Zwitterion ___ influence how proteins fold and interact • ____nature affects how amino acid are transported across cell membrane
Highly soluble pH Charge properties Zwitterionic
39
ESSENTIAL AMINO ACIDS (9)
Histidine Methionine Leucine Lysine Methionine Phenylalanine Threonine Trytophan Valine
40
CONDITIONALLY ESSENTIAL AMINO ACIDS (6)
Arginine Cysteine Glutamine Glycine Proline Tyrosine
41
Non-essential amino acids (7)
Alanine Aspartic acid Asparagine Glutamic acid Serine Selenocysteine Pyrolysine
42
The difference between polar and non polar amino acids lies in the nature of their ____ which affects how they interact with water and other molecules
side chains (R groups),
43
An amino acid that • Have SIDE CHAINS that can form hydrogen bonds • HYDROPHILIC (water loving) - they interact well with water • Often contain OXYGEN, NITROGEN or SULFUR atoms in their side chain • Found on the OUTSIDE PROTEINS, where they can interact with aqueous environment
Polar Amino acids
44
An amino acids that • Have side chains that are mostly HYDROCARBONS • HYDROPHOBIC (water fearing) - do not interact well with water • Tend to CLUSTER in the INTERIOR of proteins, away from water
Non polar amino acids
45
Ribosomes (precursor of proteins) was made in the nucleus, will be synthesized by the ____, together with ____it will be distribute in a form of ____, that will serve as the energy source inside the cells.
endoplasmic reticulum Golgi apparatus vesicles