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Flashcards in An introduction to viruses Deck (18):
1

How big are viruses?

20-400nm

2

Are viruses cellular?

No, they require a host

3

5 ways virus families are classified

- Virion shape/symmetry
- Presence/ absence of envelope
- Genome
- Mode of replication
- Host range

4

What are spike projections on the envelope useful for?

Immune system

5

Explain how the genetic information is arranged in a virus

Nucleic acid with virion associated polymerase surrounded by a protein capsid

6

Give some examples of how viruses can be transmitted

Blood borne, sexual, vertical ( hep B), faecal oral route, droplet (large particles), airborne, close contact, vector borne, zoonotic ( can lead to generation of new strain)

7

Does Hep B have immunity?

No

8

Does measles have immunity?

Yes, long term

9

Name the 3 broad categories of viral detection

- Whole organism
- Immune response to pathogen
- Part of an organism

10

Whole organism detection

Is difficult as in a cell but can use microscopy or culture in cells, tissues or animals in agar at 5% CO2

11

Immune response to pathogen detection

Antibody detection: PCR, acute/recent infection, prior infection/ response to vaccination

12

Part of an organism detection

- Antigen
- Nucleic acid
- PCR

13

Are all antiviral agents virustatic or virucidal?

Virustatic

14

Give some examples of characteristics which could mean there is a potential to eradicate a virus

No animal, no chronic carrier state and political/social support

15

Respiratory viruses

Influenza A
Rhinovirus
Respiratory syncytial virus

16

GI Virus

Rotavirus

17

Neurological viruses

Enterovirus
Herpes simplex virus

18

Tumours

HPV
Retrovirus