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Flashcards in An introduction to viruses Deck (18)
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1
Q

How big are viruses?

A

20-400nm

2
Q

Are viruses cellular?

A

No, they require a host

3
Q

5 ways virus families are classified

A
  • Virion shape/symmetry
  • Presence/ absence of envelope
  • Genome
  • Mode of replication
  • Host range
4
Q

What are spike projections on the envelope useful for?

A

Immune system

5
Q

Explain how the genetic information is arranged in a virus

A

Nucleic acid with virion associated polymerase surrounded by a protein capsid

6
Q

Give some examples of how viruses can be transmitted

A

Blood borne, sexual, vertical ( hep B), faecal oral route, droplet (large particles), airborne, close contact, vector borne, zoonotic ( can lead to generation of new strain)

7
Q

Does Hep B have immunity?

A

No

8
Q

Does measles have immunity?

A

Yes, long term

9
Q

Name the 3 broad categories of viral detection

A
  • Whole organism
  • Immune response to pathogen
  • Part of an organism
10
Q

Whole organism detection

A

Is difficult as in a cell but can use microscopy or culture in cells, tissues or animals in agar at 5% CO2

11
Q

Immune response to pathogen detection

A

Antibody detection: PCR, acute/recent infection, prior infection/ response to vaccination

12
Q

Part of an organism detection

A
  • Antigen
  • Nucleic acid
  • PCR
13
Q

Are all antiviral agents virustatic or virucidal?

A

Virustatic

14
Q

Give some examples of characteristics which could mean there is a potential to eradicate a virus

A

No animal, no chronic carrier state and political/social support

15
Q

Respiratory viruses

A

Influenza A
Rhinovirus
Respiratory syncytial virus

16
Q

GI Virus

A

Rotavirus

17
Q

Neurological viruses

A

Enterovirus

Herpes simplex virus

18
Q

Tumours

A

HPV

Retrovirus