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First Aid Hem/Onc > Anatomy > Flashcards

Flashcards in Anatomy Deck (41):
1

Life Span of RBC

120 days

2

Poikilocytosis

Varying shapes of RBCs

3

Anisocytosis

Varying sizes of RBCs

4

Erythrocytosis

polycythemia, increased hematocrit

5

Platelet dense granules

ADP, Calcium, ATP, 5-HT, histamine
platelet adhesion and vasocontriction

6

Platelet alpha granules

vWF, fibrinogen, plasminogen, PDGF
platelet derived GF

7

Life Span of Platelets

8-10days

8

Leukocyte WBC differential from highest to lowest

Neutrophils (54-62%)
Lymphocytes (25-33%)
Monocytes (3-7%)
Eosinophils (1-3%)
Basophils (0-0.75%)

9

Multilobed Nucleus, Phagocytic, acute inflammatory response

Neutrophil

10

Defensins

Neutrophil cationic protein

11

Hypersegmented Neutrophil

5 or more lobes, seen in Vitamin B12/folate deficiency

12

Increased Band cells

Immature neutrophils reflecting states of increased myeloid proliferation (bacterial infections, CML)

13

Reticulocyte

immature erythrocytes, marker of erythroid proliferation

14

Differentiates into macrophages, large, kidney-shaped nucleus. Extensive "frosted glass" cytoplasm

Monocyte

15

Monocytes that migrate into tissue

Histocytes

16

Monocyte life in blood

3 days

17

CD14

cell surface marker for macrophage

18

Important component of granuloma formation

Macrophage

19

Bilobate Nucleus

Eosinophil

20

Crystalloid Body

Eosinophil, major basic protein

21

Helps limit reaction following mast cells degranulation

Eosinophils' histaminase and arylsulfatase

22

Causes of Eosinophilia

Neoplasia, Asthma, Allergic Processes, Connective Tissue Diseases, Parasites

23

Neutralizes SRS-A of anaphylaxis

Arylsulfatase (from eosinophils)

24

Mediates Allergic Rxn, contain heparin (anticoagulant), histamine(vasodilate), and leukotrienes

Basophils

25

Bilobed nucleus that is obscured with granules

Basophils

26

has FcR for IgE to trigger release

Basophils

27

Isolated basophilia

CML

28

Cell involved in type I HS

Mast Cells

29

Cromolyn

prevents mast cell degranulation (used for asthma prophylaxis)

30

IgE cross-links upon Ag binding causing degranulation releasing histamine, heparin and eosinohpil chemotactic factors

Mast Cells

31

Highly phagocytic APC, functinos as a link between innate and adaptive immune system

Dendritic Cell

32

Dendritic cell in the skin

Langerhands cell

33

Round, densely staining nucleus with small amount of pale cytoplasm

Lymphocytes

34

Express CD19, CD20

B-lymphocyte

35

All T-cells express

CD2, CD3, CD7

36

Primary target for HIV

CD4+T helper cells

37

Co-stimulatory signal necessary for T-cell activation

CD28

38

Clock-face chromatin distribution

Plasma Cell

39

Kills virus infected and tumor cells

NK Cells

40

express CD56

NK Cels

41

Who is fucking tired?

ME!