Anatomy L.8 Flashcards
(17 cards)
What part of the breast is the most common site for breast cancer and benign lesions?
Upper outer quadrant (UOQ)
It contains the majority of the main bulk (mass)
What seperates the breast from the pectoralis major muscle?
1) pectoral fascia
2) retromammary space
What causes orange peel (pau d’ orange) appearance?
Lymphadema secondary to lympathic obstruction, commonly seen in inflammatory breast Disease
What is the clinical relevance of the retromammary space?
Precise dissection of the retromammary space allows rapid, bloodless dissection of deep aspect of breast during simple mastectomy
What is the clinical significant of orange peel appearance of the breast?
There can be an underlying malignancy or inflammatory disorder
What does the Contraction of the suspensory ligaments of cooper’s due to malignant infilteration cause?
Skin dimpling.
Carcinoma’s can decrease length of cooper’s ligaments leading to dimpling.
Fyi,
observed in conditions such as:
• Carcinoma
• Benign tumors or cysts
• Aging
• Mammary duct ectasia
• Paget’s disease of the breast
Where is the nipple in relation to the level of the thorax in most young women?
4rth intercostal
What provides the majority of the sensory innervation to the nipple of the breast?
Lateral cutaneous branches of T4
The nipple receives numerous sensory innervation from multiple spinal nerves, primarily from T4 to T6
What do lateral mammary branches originate from?
Posterior intercostal arteries (from aorta)
What is the primary drainage site of the breast?
Axillary lymph nodes
What are the first lymph nodes to receive lymphatic drainage from a breast tumor?
Sentinel lymph nodes
What are the functional secretory units within lobules?
Alveoli (acini)
What is the key functional and pathological unit of the breast?
Terminal duct lobular unit (TDLU)
What serves as histological marker of to distinguish situ from invasive carcinoma of the breast?
Myoepithelial cells (contactile cells)
What is the epithelial lining of nipple ducts?
Stratified squamous epithelium continuous with skin
What is the epithelial lining of larger ducts and lactiferous ducts?
Stratified cuboidal to columnar epithelium
What is the epithelial lining of alveoli and smaller ducts?
Simple cuboidal to columnar epithelium
