Microbiology L.1

Question 1

What functional test for ASA answers the question: Do sperms penetrate the mucus?
A. Miller-kuzrok test
B. Sperm-cervical mucus contact test
C. Sperm penetration meter
D. Sperm agglutination test
E. ELISA

Answer 1

A

Functional Tests of ASA:

1. Miller-Kurzrok Test:
   Drop of semen next to drop of cervical mucus →
   → Do the sperm penetrate the mucus? normally they can
   penetrate easily
2. Sperm-cervical mucus contact test:
   Drop of semen placed on top of drop of mucus → Forward motion? Shaking in place?
3. Sperm penetration meter:
   Mucus in capillary tube, dipped in semen → Do the sperm travel?

Question 2

What risk do antibodies to ovarian steroid cells impose?

Answer 2

Primary ovarian failure

Question 3

What can cause autoimmune ovarain failure?

Answer 3

Anti-zona pellucida antibodies

I think also anti-ovarian antibodies

Question 4

What antibodies can be found in endometriosis?

Answer 4

Anti-endometrial antibodies and anti-ovarian antibodies

Question 5

A woman present with a sudden miscarriage. This is her third miscarriage this year. Her lab results show thrombocytopenia. What could be an immunological etiology to her recurrent spontaneous misscarriage?

Answer 5

Anti-phospholipid antibody syndrome

Question 6

What is the mechanism of action of APA?

Answer 6

Vasoconstriction in placenta
Platelet damage
Platelet bind to vascular endothelium
Platelet aggregation
Local thrombosis
Inhibition of trophoblast formation
Damage to trophoblast