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Flashcards in Anemia due to underproduction Deck (8):
1

Anemia characterized by a low corrected reticulocyte count…

Anemia due to underproduction

2

What can infect progenitor red cells causing a temporary stop to erythropoiesis, which leads to significant anemia in the setting of a preexisting marrow stress?

Parvovirus B19

3

What anemia is caused by damage to hematopoietic stems cells?

Aplastic anemia

4

What is seen on biopsy of a patient with aplastic anemia?

Empty, fatty marrow

5

Pancytopenia and a low reticulocyte count are seen within the setting of aplastic anemia. What is the underlying cause of these findings?

Damage to hematopoietic stem cells

6

What are the causes of aplastic anemia?

Drugs
Chemicals
Viral infections
Autoimmune damage

7

How will immunosuppression help with some aplastic anemias?

Some idiopathic cases of aplastic anemia are due to abnormal T-cell activation with release of cytokines

8

What is a myelophthisic process?

Pathological process involving the replacement of bone marrow causing hematopoiesis impairment and pancytopenia