Anti naeusa drugs

Question 1

where does Nasua come from?

Answer 1

chemo receptor trigger zone (brain)

Question 2

Serotonin 5-HT3 antagonists are?

Answer 2

is a neurotransmitter

Question 3

Serotonin 5-HT3 antagonists examples?

Answer 3

ondansetron (Zofran) -pretty strong
-route: sublingual

Question 4

what is the #1 side effect of Serotonin 5-HT3 antagonists ?

Answer 4

headache

Question 5

MOA of Serotonin 5-HT3 antagonists >

Answer 5

blocks action of serotonin

Question 6

which Serotonin 5-HT3 antagonists medication is given to cancer pt?

Answer 6

palonsetron (Aloxi)

Question 7

Phenothiazines are?

Answer 7

neuroleptics (work on CNS system)

Question 8

examples of phenothiazine?

Answer 8

chlorpromazine (thaorazine)
-> can be used for hiccups and anti-psyc med
procholdrperazine (compazine)

Question 9

what are the side effects of phenothiazine

Answer 9

EPS effects (unwanted movement problems) and restlessness

Question 10

what is the MOA of phenothiazine

Answer 10

acts in CNS level of chemoreceptor trigger zone
-blocks dopamine receptors

Question 11

Antihistamines examples

Answer 11

meclizine (antivert) –> for vertigo (inner ear problem)
diphenhydramine (benadryl)

Question 12

Prokinetic Agent example?

Answer 12

metoclopraimide (reglan)
-CAUSE diarrhea
-MOA: stops action of dopamine

Question 13

anticholingergic example?

Answer 13

trimethobenzamide (tigan)
MOA: blocks cholingeric pathways to vomiting center

Question 14

Butyrophenone example?

Answer 14

droperidol (inapsine)

Question 15

corticosteroids example?

Answer 15

dexmethasone (decadron)
-strong and expensive

Question 16

cannabinoids is called?

Answer 16

tetrahydrocannabinol (TCH)

Question 17

what are the 8 anti-naseua drugs?

Answer 17

serotonin 5-HT3, phenothiazines, antihistamines, prokinetic agents, anticholingeric, butyrophenone, corticosteroids, cannabinoids