Antiarrhythmics Flashcards Preview

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Flashcards in Antiarrhythmics Deck (10):
1

Class I antiarrhythmics in general

Are Na channel blockers. Toxicity made worse by hyperkalemia

2

Class 1A Antiarrhythmics

Quinidine procainamide disopyramide

Lengthen action potential, increase ERP. Lengthen QT.

3

Class 1A antiarryhtmics side effects

Cinchonism, SLE-like snydrome, TORSADES de POINTES

4

Class 1B antiarrythmics

Lidocaine, Mexiletine

Decrease action potential duration.

BEST FOR POST MI ARRHYTHMIA PROTECTION

5

Class IC antiarrhythmics

Flecainide, Propafenone

Don't change length of action potential. Increase refeactory period. Contraindicated in ischemic and structural HD

6

Class II antiarrhythmics

Beta blockers
Increase the length of class IV of the SA and AV node action potential. Increase PR interval because AV node is particularly sensitive.

TREAT OVERDOSE WITH GLUCAGON

7

Class III antiarrythmics

Amiodarone, Ibutilide, dofetilide, sotalol

K blockers. LEngthen AP duration, increase QT.

8

Class IV antiarrhythmics

CCB
Decrease conduction velocity. Increase pr interval. Cause constipation flushing edema

9

Adenosine

Increase K outflow, prevent Ca inflow. Abolish SVT. Very short acting.

10

How to abolish torsades

Mg2+