Drug reactions Flashcards Preview

STEP 1 Pharm > Drug reactions > Flashcards

Flashcards in Drug reactions Deck (30):
1

Coronary vasospasm

Triptans, ergots, cocaine

2

Cutaneous flushing

Vancomycin, adenosine, niacin, CCBs

3

Dilated cardiomyopathy

Alcohol, doxo/daunorubin,

4

Torsades de points

Type III antiarrhythmics, class 1a antiarrhythmics, macrolides, tricyclics, antipsychotics.

5

Adrenocortical insufficiency

glucocorticoid withdrawal

6

Hot flashes

Tamoxifen, clomiphene

7

Hyperglycemia

Tacrolimus, protease inhibitors, niacin, HCTZ, beta blockers, corticosteroids

Taking pills necessitates having blood checked

8

Hypothyroidism

Lithium, amiodarone, sulfonamides

9

Acute cholestatic hepatitis

Erythromycin, also causes jaundice

10

Diarrhea

Metformin, erythromycin, colchicine, orlistat, acarbose

11

Hepatic necrosis

Halothana, amantin, valproate, acetaminophen

12

Hepatitis

Isoniazid

13

Pancreatitis

didanosine, coricosteroids, alcohol, valproate, azathioprine, diuretics

14

Pseudomembranous colitis

Clindamycin, ampicillin, cephalosporins

15

Agranulocytosis

Dapsone, clozapine, carbamazepine, colchicine, methimazole, propylthiouricil

"Drugs CCCrush Myeloblasts and Promyelocytes"

16

Aplastic anemia

Carbamazepine, methimazole, nsaids, benzene, chloramphenicol, propylthiouracil

17

Coombs positive hemolytic anemia

methyldopa, penicillin

18

Gray baby syndrome

Chloramphenicol

19

Hemolysis in g6pd

Sulfa drugs, fava beans, isoniazid, primaquin

20

Megaloblastic anemia

phenytoin, methotrexate, sulfa drugs

21

Fat redistributioin

protease inhibitors and glucocorticoids

22

gingival hyperplasia

Phenytoin, verapamil, cyclosporine, nifedipine

23

Hyperuricemia

Pyrazinamide, thiazides, furosemide, niacin

24

Steven's Johnson syndrome

Antiepileptics, allopurinol, sulfas, penicillin

25

Sle like syndrome

Sulfa drugs, hydralazine, INH, phenytoin, etanercept

26

CYP inducers

Modafinil

C - carbamazepine
Rifampin
A
Phenobarbital

Griseofulvin
Phenytoin
St john's wort

Nevirapine

27

CYP substrates

Antidepressants
antipsychotics
antiepileptics
Anesthetics
Theophylline
Warfarin
Statin
OCP

28

CYP inhibitors

Acute
Gemfibrozil
Ciprofloxacin
Isoniazid
Grapefruit juice
quinidine
amiodarone
ketoconazole
Macrolides
Sulfonamides
Cimetidine
Ritonavir

29

Sulfa drugs

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamides, sulfonylureas, sulfazalazine

30

Sulfa drug allergy

Can cause SJS, fever, hemolytic anemia, thrombocytopenia, agranulocytosis, and hives.