antiarrythmic 2 Flashcards Preview

Pharm Unit 4 by Hans Kim > antiarrythmic 2 > Flashcards

Flashcards in antiarrythmic 2 Deck (6)
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1

what drug has stronger K+ channels blocker than beta adrenergic receptor antagonist?

sotalol

2

what has the multiple actions on Na, K, Ca channel blockers or alpha, beta receptor antagonist?

amiodarone

3

what is the mech of class IA?

fast Na+ channel blocker
--> prolongs effective refractory period
--> prolongs action potential duration

4

what is the alternative drug for chronic treatment of atrial flutter, fibrillation, SVT?

Quinidine

5

what other effects do quinidine have?

1. alpha adrenergic blockade
2. M2 blockade
3. vagal inhibtion

6

what are the toxicities of class IA?

1. diarrhea
2. nausea
3. fever
4. hepatitis
5. thrombocytopenia
6. cinchonism
7. QT prolongation