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Pharm Unit 4 by Hans Kim > clinical case HTN > Flashcards

Flashcards in clinical case HTN Deck (11)
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1

what is prehypertension?

blood pressure 120/80 to 139/89 mmHg

2

is drug therapy recommended for prehypertension?

no (evidence lacking on whether it decreases or prevents cardiovascular events)

3

what are the clinical bottom line for HTN?

1. cardiovascular risk increases as blood pressure increases
2. screen all adults for hypertension at 1 to 2 yr intervals
3. lifestyle modification can delay hypertension + CVD onset
--> no evidence for adding pharmacotherapy for prevention

4

drug therapy for volume overload?

thiazide, loop diuretic, aldosterone antagonist

5

drug therapy for sympathetic overactivity?

beta blocker --> use to counteract reflex tachycardia from vasodilators or in heart failure

6

drug therapy for increased vascular resistance?

ACEi or ARB

7

drug therapy smooth-muscle contraction?

dihydropyridine CCB, beta blocker, hydralazine

8

DOC for recurrent stroke prevention?

diuretic, ACE inhibitor

9

DOC for chronic kidney dz?

ACE inhibitors, ARB

10

what are the advantages of combination therapies?

1. better adherence
2. may cost less for pts than individual prescriptions

11

what is a good initial therapy if bp is higher than 160/100?

ACEi / ARBs + hydrochlorothiazide