Antibiotics Flashcards

1
Q

HIV prophylaxis should begin w/i ____ of the exposure

A

72 hours

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2
Q

Toxoplasmososis is transmited by:

A

Cats

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3
Q

serious side effect of Sulfa is:

A

Steven Jonhons Syndrome

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4
Q

tx for Strep Throat in a pt with penicillin allergy is:

A

Clindamycin and clarithromycin

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5
Q

alcohol is contraindicated when taking what abx?

A

Metronidazole

Tinidazole

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6
Q

tx for Group B pneumonia is:

A

Penicillin

Ampicillin

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7
Q

resistance to penicillins is through:

A

Beta lacatmase secreted by bacteria

destroy Beta lactam rings

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8
Q

tx for C Diff:

A

oral metronidazole

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9
Q

organism that causes Rocky Mountain Spotted Fever

A

Rickettsia rickettsii

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10
Q

abx that inhibit topoisomerase is

A

Fluoroquinolone’s

FLORO=TOPO

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11
Q

Psuedomonas aeruginosa

A

ciprofloxacin

levofloxacin

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12
Q

important toxicities with Aminoglycosides:

A

Ototoxicity

and

Nephrotoxicity

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13
Q

diagnostic / confirmatory syphilis test is

A

fluorescent treponemal antibody absorption

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14
Q

acute fluctuating weakness along with onset of double vision and inability to focus on near objects

sx of:

A

Botulinum toxin

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15
Q

CD4<200 requires prophylaxis of:

A

PCP

with TMP-SMX (bactrum)

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16
Q

typical HIV tx protocol

A

2 NRTI + a choice of:

NNRI

PI

INSTI

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17
Q

Borrelia burgdorferi is:

A

Lyme Disease

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18
Q

tx for uncompleted cystitis is:

A

3 day flouroquinolone

or

5 day nitrofurantoin

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19
Q

tx of otitis media in a pt with penicillin allergy is:

A

Erythromycin

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20
Q

tx for Rabies:

A

immunoglobulins (5 day series)

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21
Q

Vancomycin side effects:

A

Ototoxic

Nephrotoxic

Red man syndrome

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22
Q

Tx for PUD is:

A

PPI + Clarithromycin + Amoxicilin

or

PPI + Metronidazole + Tetracycline

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23
Q

tx for Rocky Mountain Spotted Fever in a pregnant pt is:

A

Chloramphenicol

Doxycyclin in a non pregnant

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24
Q

Neurological Sx seen in Lyme Disease:

A

Bell’s palsy (CN VII)

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25
ABX contraindicated in pregnancy: FAST
**F**luorquinolones (joints, tendons) **A**minoglycosides (audotory) **S**ulfonamide (jaundice) **T**etracyclines (teeth/bone problems)
26
most dangerous type of malaria is:
***P falciparum***
27
rash that began at the **wrist or ankle** is a sign of:
**Rocky Mountain Spotted Fever** ***climing the mountaing with wrist and ankle***
28
Primary agent to treat **MRSA** is:
**Vancomycin** **Linezolid**
29
which group of pt ceftriaxone is contraindicated for:
**neonates** causes: biliary sludging, displaces bilirubin\>**kernicterus**
30
**parasite in the RBC** are known as
Malaria
31
cicrular red papule centrifugal spread central clearing bull's eye all known as **Erythema migrans** discriptive of:
**Lyme Diz - stage I** **Erythema Limgrans**
32
MoA **Vancomycin**
Inhibit Cell Wall Production
33
Diangosing method for Lyme disease:
**IFA** **ELISE**
34
India ink Stain is used to diagnose
***Cryptococcus*** Indian Cryptococcus
35
Typhoid Fever Constipation or diarrhea signs of:
***Salmonellosis***
36
**Lyme** disease is transmitted by:
Deer tick ## Footnote **Dear Lyme**
37
most important toxicity associated with antifungals is:
**Hepatic toxicity**
38
STD tx:
Azithromycin Ceftriaxone Doxycycline **STD=ACD**
39
Red Man Syndrome is caused by:
**Vancomycin**
40
Most common intestinal wam is:
**Ascariasis** ASS
41
because **Sulfa** drugs inhibit **folate synthesis**, they are contraindicated in:
**Pregnancy**
42
Prophilaxis of Cryptococcal meningitis when CD4\<200 is:
Flucanazole cryptococcus is a fungi
43
**Photocensitivity** is produced by:
Flouroqinalones ## Footnote **Cyclins**
44
Cryptococcal meningitis is seen in pt's with:
HIV
45
**Fluoroquinolone**s are contraindicated in:
**Long QT syndrome**
46
tx for CMV is:
**Ganciclovir**
47
**bats**, raccoons bite may transmit
**Rabies**
48
**Disulfiram** reaction is:
occurs if **alcohol** is taken concurrent with **metronidazole**
49
**Sulfa** drugs lead to the increase in:
**K** therefore can not be combined with ACE-I
50
**Sulfa** drugs MoA
inhibit **Folic Acid** ## Footnote **Folic Sulfa**
51
**screening** syphilis test is:
PRP
52
**2nd line** of treatment of **otitis media** is:
**Augmentin** Cephalosporin
53
Tx for Lyme and Rocky Mount Spotted Fever both transmitted by ticks:
**DOXYCYCLINE**
54
**Pinicilins** MoA
**bind to penicillin binding protein to _inhibit cell wall synthesis_**
55
diagnose/confirm HIV with
**Western Blot**
56
CD4\<100 requires prophylaxis of:
***Toxoplasmosis*** with **TMP-SMX** (bacturm) **CTO=TOXO**
57
**Penicillin** may cross react with
**Cephalosporins**
58
important side effect of **Macrolides**:
Long QT **warfarin interaction\>bleeing** Ototoxic
59
**metalic taste** is produced by what medication:
Clarithromycin ## Footnote **clear metal**
60
Tabes Dorsalis refers to:
Neuro Syphilis
61
tx for toxoplasmosis encephalitis is:
**Pyrimethamine**
62
CD4\<50 requires prophylaxis of:
***Mycobacterium*** with ## Footnote **Azithromycin**
63
**Photosensitivity** is caused by:
Doxycycline TMP/SMX (bactrum) Ciproflaxin Photo=BCD
64
Penicillin coverage include:
good for Strep poor for Staph (resistent) poor coverage of - organisms good anaerobe coverage
65
Penicillin **hypersensitivity** refers to:
Hive: **maculopapular rash**
66
organism that cause travel diarrhea:
***E. Coli*** ***Shigella*** ***Campylobacter jeujuni***
67
**thick gray pseudomembane** in the throat is a signs of:
**Diphtheria**
68
dangerous **Penicillin** adverse reaction:
**_anaphylactic reaction_** mediated through **IgE** antibodies
69
most common side effeect of **Augmentin** is:
**Diarrhea** **Bite augmenting\>Diarrhea**
70
**Augment** is:
**Amoxicillin + Clavulanate**
71
MoA of Tetra**cycline**
**inhibit protein synthesis** **cyclines inhibit protein synthesis**
72
abx most known to cause *_C Diff:_*
**Clindamycin**
73
abx of choice for **Human/Animal bites** is:
**Augmentin** **Augmentin=Bugmentin**
74
tx for ***Clostridium Botulinum*** is:
botulinum antitoxins
75
what is Amino Penicillins coverage | (ampicillin, amoxicillin)
good + coverage ## Footnote **_some negative coverage (unlike penicillin)_**
76
tx for **Step pneumo**, pneumonia in kids is:
**Amoxicillin** **Penicillin** **Cephalosporin**
77
important consideration for pt with mononucleosis (EBV) is:
abstain from contact sports due to high risk of spleen rapture
78
tx for **bacterial sinusitis** in a pt who is allergic to penicillin:
**Doxycycline 1 st line** **Moxifloxacin 2 nd line**
79
Pneumonia in pregnancy should be treated with?
**Erythromycin**
80
tx for bacterial sinusitis is:
**Augmentin (Amoxicillin-clavulanate)**
81
mainstay tx for ***Cholera*** is:
water replacement
82
tx for MSSA
**nafcicillin** **dicloxacillin** **m**_SS_**a=ci**_LL_**in**
83
84
Shigellosis will produce what kind of diarrhea
Bloody ## Footnote **Bloody shigellosis**
85
**Rice water** stool is associated with:
**Vibrio Cholera**
86
**Treponema pallidum** is: corkscrew-shaped spirochete
Syphilis
87
Diarrhea due to drinking of **mountain water** is usually caused by what organism:
***Giardia lamblia***
88
1st line of treatment of **otitis media** is:
**Amoxicillin**
89
pt becomes infected with Lyme Dz only if the tick remains on the skin for more than
**24 hours**
90
**Disulfiram reaction** includes:
skin flashing accelerated heart rate SOB N/V Headaches
91
the only cephalosporin that is eliminated through HepatoBilliary system is:
**Ceftriaxone**
92
Cardiac Symptoms of Lyme Dz is:
**AV blocks**
93
tx for **Pinwarms**
**albendazole** **mebendazole**
94
**Painless ulcer / chancer** on the genitals is a sign of:
**Primary syphilis**
95
Tx for Diverticulitis is:
Ciproflaxcin + metronidazole
96
#1 cause of AIDS-associated blindness is caused by:
Cytomegalovirus **CMV=retinitis**
97
tx for Rocky Mountain Spotted Fever is:
**Doxycycline**
98
first manifistation of Lyme Dz is:
**Erythema Migrans**
99
Wood or dog ticks transmitt?
**Rocky Mountain Spotted Fever**
100
wart-like lesions on the genitals seen in syphilis are known as:
**Condylamata lata**
101
most common organism producing bacterial prostatitis:
E.Coli Proteus
102
103
tx for **Syphilis:**
**Pencilllin** **_syPhilis=Pencillin_**
104
**orange-red body fluids** caused by:
**Rifampin**
105
**+ Heterophile agglutination** test is known as:
Mono test indicative of EBV
106
diagnosing method for Malaria is:
**peripheral smear**
107
MoA of **Macrolides**
**inhibit protein synthesis**
108
primary syphilis sx:
painless chancre ## Footnote **primary=painless**
109
**Periodical** chills/fever/sweats is typical for
**Marlaria** presentation
110
Tx for bacterial prostatitis:
Cipro (for gram -) Ampicillin (for gam +)
111
most Peniceillins are eliminated through
**Renal System** **P**enicillin=**P**enal elimination
112
screening HIV is with:
ELISA _HIV scr**EE**n with **E** lisa_
113
tx of **Strep Throut in conjunction with Mono** is:
**Penicillin or erythromycin**
114
what effect **Rifampin** has on INR
**decreases**
115
tx for **Bacterial Candidosis** is:
**Micnonazole**
116
Cephalosporins MoA is:
**Beta lactam inhibitors**
117
**condylomata lata** corresponds to:
**secondary syphilis**
118
Pinworms dx is:
scotch tape
119
**bilateral cranial nerve palsies** descending symmetrical weakness respiratory paralysis signs of:
**Botulism**
120
**multiple ring lesion** on brain CT of an HIV pt are indicative of
**Toxoplasma Encephalitis**
121
1st line tx for Strep Throat:
**Penicillin V** **Amoxicillin**
122
tx for intestinal worms is:
**albendazole**
123
**Cryptosporidium** is usually found in:
**swimming pools**
124
Chlamydia:
**Azithromycin + doxycycline** **+ ceftriaxone (for Gonorrhea)**
125
side effects of HIV drugs: NRTI NNRTI Fussion inhibitors Protiease inhibitors INSTI
NRTI - **anemia** NNRTI - **rash, neuro** Fussion inhibitors - i**njection site pain** Protiease inhibitors - **lipid abn** INSTI - **headache**
126
important side effect of **Fluorquinolones**:
**Tendon Rapture** **Photosinsitivity=Fluoro** **Long QT** **Contraindicated in children and pregnancy**
127
most **wide spectrum of antifungal coverage** is:
**amphoterocin**
128
Teeth discoloration is produced by:
Tetracyclines ## Footnote **Teeth discoloratio = TEETHRACycline** **contraindicated in children \>8 y.o**
129
Late Lyme Dz is manifested by:
**Chronic Arthritis**
130
what can **reduce the efficacy of Flouroquinolones**
**Chelattion by Mg, Ca, Al, Multivitamins, Zn**
131
most common **Cephalosporins** adverse reaction is:
**GI: N/V**
132
Amoxicillin given to a pt with Mono may result in:
**Maculapapular Rash**
133