Antibiotics Flashcards Preview

Disease and Defense Mine > Antibiotics > Flashcards

Flashcards in Antibiotics Deck (26):
1

penicillin

CW synth. blocker
beta lactam antibiotic
elimination: renal
V version: acid stable
G version: prototype

2

dicloxacillin

CW synth. blocker,
penicillinase resistant
beta lactam antibiotic
elimination: renal

3

amoxacillin/ampicillin

CW synth blocker
beta lactam antibiotic
elimination: renal

4

amox/clav

CW synth blocker
penicillinase resistant
beta lactam antibiotic
elimination: renal

5

pip/tazo

CW synth blocker
penicillinase resistant
beta lactam antibiotic
admin: IV ONLY
elimination: renal

6

cephalexin (po)
cefazolin (IV)

1st gen
CW synth blocker
beta lactam antibiotic
elimination: renal

7

cefuroxime

2nd gen
CW synth blocker
beta lactam antibiotic
elimination: renal

8

ceftriaxone

3rd gen
CW synth blocker
beta lactam antibiotic
admin: IV ONLY
elimination: renal
gonorrhea activity

9

ceftazidime

3rd gen
CW synth blocker
pseudomonas activity
beta lactam antibiotic
elimination: renal

10

cefepime

4th gen
CW synth blocker
beta lactam antibiotic
elimination: renal

11

ertapenem

carbapenem
CW synth blocker
beta lactam antibiotic

12

imip, dori, mero

carbapenem
CW synth blocker
beta lactam antibiotic

13

vancomycin

CW synth blocker
admin: IV only except in entero-infections

14

macrolides

protein synth blocker
azithromycin, clarithromycin, erythromycin
Unique activity: mycoplasma
Interactions: clar & ery drug-drug interactions due to inhibition of P450

15

tetracyclines

protein syn blocker
doxycycline- non-renally emlinated tetracycline, can lead to candidal overgrowth
adverse effects: candidal overgrowth
elimination: renal
unique activity: mycoplasma

16

clindamycin

protein syn blocker
adverse reaction: C. difficile diarrhea
elimination: non-renal

17

chloramphenicol

protein syn blocker
greyed out on chart

18

aminoglycosides

protein syn blocker
BACTERICIDAL- irreversibly bind ribosome
admin: IV only
elimination: renal

19

ciprofloxacin

fluoroquinolone
DNA syn blocker
elimination: renal, but is non-substrate inhibitor of P450 (caffeine-theophylline)

20

levofloxacin

fluoroquinolone
DNA syn blocker

21

moxifloxicin

fluoroquinolone
DNA syn blocker

22

nitrofurantoin

DNA syn blocker

23

metronidazole

DNA syn blocker
Interactions: with alcohol due to inhibition of aldehyde metabolism

24

protein synthesis blockers

typically bacteriostatic

25

CW synth inhibitors

typically bactericidal

26

DNA inhibitors

typically bactericidal