Antibiotics / Microman (2018) / Microbiology Summary Flashcards Preview

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Flashcards in Antibiotics / Microman (2018) / Microbiology Summary Deck (111)
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1

If you're looking for specific antibiotic treatments then go onto 'The Holy Grail (Treatments)' Brainscape subject, and see the deck 'Infections'. This specific deck will be for general microbiological facts you need to know to understand Antibiotics. It will also cover themes of Tayside Microman 2018.

WANSUM?

2

Side effects of Gentamycin?

- Renal damage
- Damage to CN VIII (deafness and dizziness)

3

What family of antibiotics are best known to cause erythema (redness)

Cephalosporins

4

Purple
Stains well due to thick peptidoglycan wall

Gram positive

5

Pink
Has a thin peptidoglycan wall

Gram negative

6

Exotoxin exported from the cell wall

Gram positive

7

Endotoxin is part of the cell wall

Gram negative

8

Gram positive chain

Streptococci

9

Test for Streptococci?

Haemolysis

10

Alpha haemolysis colour

Partial haemolysis: Green

11

Beta haemolysis colour

Complete haemolysis: Yellow/ translucent

12

Gamma haemolysis colour

No haemolysis: Red

13

Alpha haemolysis organisms

Strep pneumoniae
Strep viridans

14

Beta haemolysis organisms

Strep (A) pyogenes
Strep B

15

Gamma haemolysis organisms

Enterococcus faecalis (Strep D)

16

What diseases does Strep pyogenes most commonly cause?

Strep throat
Rheumatic fever
Acute glomerular nephritis
Scarlet fever

17

What diseases does Strep viridans most commonly cause?

Endocarditis- post dental treatment

18

What diseases does Enterococcus faecalis most commonly cause?

It's a harmless commensal- but can cause intra-abdominal infections if it gets into the peritoneum.

19

What organisms usually cause bacterial meningitis in newborns

Strep B

20

What are the two most common organisms that cause bacterial meningitis is adults and children?

Neisseria meningitidis
Strep pneumoniae

21

Gram positive clusters

Staphlococci

22

Test for Staphlococci?

Coagulase test

23

Positive coagulase Staph

Staph Aureus

24

Negative coagulase Staph

Staff epidermidis
Skin commensals

25

What does Methicillin-resistant Staph Aureus (MRSA) produce?

Panton valentine leucocidin
This causes necrolytic skin infections

26

Gram positive bacilli (rods) organisms?

Clostiridium difficile
Bacillus cereus
Listeria monocytogenes
Saccharopolyspora rectivirgula
Others

27

What toxins does C. difficile release?

Enterotoxin A
Cytotoxin B
When stressed- spores that can withstand extreme conditions

28

How are the investigations for C. difficile?

Stool culture
Bacterial DNA/ toxin

29

What are the four antibiotics that lead to C. difficile

Ciprofloxacin
Co-amoxiclav
Clindamycin
Cephalosporins (Ceftriaxone)

30

How does one catch bacillus cereus?

From eating reheated rice