Antidepressant Agents Flashcards Preview

Mo-Neuro 4 > Antidepressant Agents > Flashcards

Flashcards in Antidepressant Agents Deck (16):
1

NT: Monoamine Neurotransmitter Brainstem Nuclei
NE--> Locus Ceruleus
5HT --> Raphe
DA--> VTA

NT: Monoamine Neurotransmitter Brainstem Nuclei
NE--> Locus Ceruleus
5HT --> Raphe
DA--> VTA

2

Initial observation: Reserpine depleted brain NE and 5HT -->

induced depression

3

Additional support: Effective antidepressant drugs share property to ___________

enhance NE-5HT-(DA) availability in synapse

4

Antidepressant Agents

Sertraline (Zoloft®) SSRI
Citalopram (Celexa®) SSRI
Escitalopram (Lexapro®) SSRI
Fluoxetine (Prozac®)  SSRI
Venlafaxine (Effexor XR®) SNRI
Trazodone 5HT partial agonist-SSRI
Duloxetine (Cymbalta®) SNRI
Paroxetine (Paxil®) / (Paxil CR®) SSRI
Amitriptyline (Elavil®) TCAD
Bupropion (Wellbutrin XL®) NDRI

5

Mirtazapine (Remeron®)

α2 antagonist
Phenelzine MAOI

6

Sertraline (Zoloft®)

SSRI

7

Citalopram (Celexa®)

SSRI

8

Escitalopram (Lexapro®)

SSRI

9

Fluoxetine (Prozac®)

SSRI

10

Bupropion (Wellbutrin XL®)

NDRI

11

Amitriptyline (Elavil®)

TCAD

12

Paroxetine (Paxil®) / (Paxil CR®)

SSRI

13

Trazodone

5HT partial agonist-SSRI

14

Duloxetine (Cymbalta®)

SNRI

15

Venlafaxine (Effexor XR®)

SNRI

16

Fluoxetine (Prozac®)

SSRI