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Flashcards in Mood Disorders Deck (11):
1

Epidemiology of depression

50% in treatment
Age if onset: 30
18-44 highest rate
Risks: unemployed, separated, divorced, urban, female

2

WHO estimates depression affects _________ people worldwide, and is projected to increase
The US has similar rates with the world

~ 120 million

Anxiety is the most common mental disorder
Mood disorders (depression, bipolar) also very prevalent

3

Depression Pathophys unknown
NOT a __________________
No single area of brain pathology
Likely involves alterations in neural circuitry

“chemical imbalance”

4

Pts sleep and eat more
Lead limbs / lead paralysis
mood reactivity, leaden paralysis, reverse neurovegetative symptoms (increased appetite, weight gain, hypersomnia)

Atypical depression

5

Often with auditory hallucinations, nihilistic delusions

psychotic depression

6

More depressed in the morning
mood worse in the morning, early morning awakening, anorexia, weight loss, guilt, psychomotor retardation

melancholic

7

Mood typically worsens in the fall and winter, improves in the spring and summer.

Seasonal Affective

8

Bipolar disorder is best considered on a spectrum, ranging from extreme mood swings to cyclothymia to hypomanias + major depression (Bipolar II) to frank manias (Bipolar I).

Manias can be induced by medications (most often ________) or brain injuries (secondary manias)

antidepressants or steroids

9

disorder involves periods of severe mood episodes from mania to depression

Bipolar 1
more severe

10

hypomania that alternate with periods of severe depression.

Bipolar 2

11

Discuss risk factors for suicide, demographics, and epidemiology.

• 1.4% all deaths in US and the 11th leading cause of death all ages
• 2nd leading cause of death 25-34 year olds
• In the US, ~ 300,000 attempts and 33,000 completed suicides per year.
• 10-15% of patients with severe MDD suicide
• 4:1 Male:Female suicide ratio
• 79 % of those who commit suicides are men
• Women attempt suicide 2-3X more often than men
• 2/3 of all completers had contact with PCP within a month of their suicide
• 56-75% of first attempts end in death
• 3-7% of all attempters will eventually kill themselves