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Pharmacology > Antidepressives > Flashcards

Flashcards in Antidepressives Deck (32):
1

What is the most important question to ask a pt c depression?

Do you have a any suicidal thoughts?

2

What s/s does one have to display & for how long?

5 must be present for minimum of 2 wk.
1. Difficulty sleeping/sleeping too much
2. Extremely tired/ w/o energy
3. Vague physical symptoms
4. Inability to concentrate/make decisions
5. Feeling of despair, guilt, misery, lack self worth
6. Obsessed c death
7. Lack of interest in personal appearance/sex
8. Delusions or hallucinations

3

RN Role for depression

1. Obtain Hx
2. R/O medical & neurological causes
3. Ask about suicidal ideation
4. Obtain family Hx
5. Obtain v.s., liver/renal functions, Cardiovascular status, body wt.
6. Monitor therapeutic blood levels

4

RN Education for depression

1. Provide diet education about food that contain tyramine (MAOI)
2. Provide info on s/s of dehydration
3. Provide med education.

5

Anitdepressants general points

1. Medical Dx- chemical imbalance or seratonin, dopamine, norepinephrine.
2. Medication attempts to correct imbalance
3. avoid alcohol
4. Take 1-4 weeks for therapeutic effect
5. DO NOT DC ABRUPTLY

6

RN Implication for depression

1. Monitor v.s.
2. Monitor neurologic & cardiovascular status
3. Typically SNS response:
Dizziness. headache, tremor, N/V, anxiety, disorientation, hyperflexia, daphoresis, fever.

7

Name 3 lines of antidepressants:

1. Tricyclic
2. SSRI
3. MAOI

8

Tricyclic mechanism of action:

1. Decrease reabsorption of norepinephrine & serotonin
2. Corrects imbalance in neurotransmitter concentration

9

Name 2 Tricyclic medications

1. Elavil
2. Tofranil

10

What do Elavil and Tofranil Tx?

1. Major depression
2. Panic attacks
3. OCD

11

Side effects of tricyclic's

1. Seizures
2. OD
3. Dry mouth
4. Urinary retention
5. Tremors
Another words=SNS response

12

RN Implication & Teaching for TCA's

1. Take 2-4 weeks for therapeutic effect
2. Avoid smoking
3. Take @ bed time
4. Orthostatic hypotension
5. Suck on candy for dry mouth

13

In order, what are the safest antidepressants to use, 1 being safest 3 being most dangerous?

1. SSRI
2. MAOI
3. Tricyclic

14

What are some contraindications for TCA's?

1. BPH
2. Dysrhythmias
3. Seizures
4. Narrow-angle glaucoma

15

Name 1 SSRI medication

1. Zoloft

16

What is SSRI mechanism of action?

Inhibits serotonin reuptake

17

What do SSRI's Tx?

Depression

18

What are some Adverse Effects of SSRI?

1. Agitation
2. Jitters
3. Anxiety
SNS Response
4. Decrease in REM sleep

19

RN Implication & Teaching for SSRI

1. DO NOT START W/I 2 WEEKS OF MAOI
2. Monitor hepatic function
3. Monitor seizure disorder
4. Avoid alcohol, OTC meds, Herbs
5. Take 1-4 weeks to achieve therapeutic effect

20

Name 1 MAOI

1. Nardil

21

MAOI mechanism of action

Limit breakdown of norepinephrine, Dopamine & Serotonin

22

What do MAOI Tx?

Depression

23

What are some Adverse Effects of MAOI?

1. Orthostatic hypotension
2. Sexual dysfunction
3. Wt gain

24

RN Implication & Teaching for MAOI

1. Keep CCB @ bedside as ANTIDOTE!
2. Avoid foods high in tyramine & caffeine. Can lead to HTN crises.
3. Mmonitor suicidal ideation
4. Avoid alcohol

25

Name 4 classification of meds used for antianxiety.
1 being the most used 4 being least used

1. Benzodiazepine
2. Barbiturates
3. Antidepressants
4. Nonbenzodiazepines/Nonbarbiturate CNS depressants

26

Name 2 Benzodiazepines used for anxiety

1. Ativan
2. Valium

27

What are mechanism of action for benzodiazepines?

Changing action of GABA

28

What do benzodiazepines Tx?

1. Short-term seizures
2. anxiety

29

RN Implication & Teaching for Benzodiazepine

1. Monitor respiration
2. Tolerance may develop
3. Assess for suicidal tendancy
4. DO NOT USE IN GLAUCOMA PT.

30

Antidote for Benzodiazepine

Romazicon

31

What are some contraindications for benzodiazepines?

1. Narrow-angle glaucoma
2. Acute alcohol intoxication
3. Children under 12
4. Renal & Hepatic dysfunction
5. Pregnancy & Lactation

32

What are some Adverse Effects for benzodiazepines?

PNS reaction
1. Drowsiness
2. Cardio irregularities
3. Constipation
4. Physical dependence