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Flashcards in Antihelminthic Deck (25):
0

Coverage of albendazole

Ascariasis
Ancylostoma
Necator
Capillariasis

1

DOC for trichuris

Mebendazole

2

DOC for strongyloides

Ivermectin

3

DOC for enterobius

Pyrantel pamoate

4

DOC for filariasis

DEC

5

DOC for trichinella

Thiabendazole

6

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

Mebendazole

7

Inhibits microtubule assembly

Albendazole

8

Intensifies GABA-mediated neurotransmission in nematodes

Ivermectin

9

Stimulates nicotinic receptors at NMJ of nematodes

Pyrabtel pamoate

10

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

Thiabendazole

11

Invreases membrane permeability to calcium causing muscle paralysis, vacuolization and death

Praziquantel

12

Uncouples oxidative phosphorylation by activating ATPases

Niclosamide

13

Differentiate mebendazole, thiabendazole and albendazole in terms of _-cidal

Meb: Ovicidal
Thia: Ovicidal
Alb: Larvicidal and ovicidal

14

DOC for echinococcus

Albendazole

15

Mazzoti reaction is seen in

DEC in filariasis
Ivernmectin in strongyloidiasis

16

Contraindicated in pregnancy

Mebendazole
Thiabendazole

17

Contraindicated in patients with hepatic dysfunction

Pyrantel pamoate

18

Praziquantel is used with _ in treating neurocysticercosis

Corticosteroids

19

CI of praziquantel

Ocular cystecircosis

20

Alternative drug for cestode infection

Niclosamide

21

Kills scolices and cestode segments but has no effect on ova

Niclosamide

22

Avoid _ with niclosamide

Alcohil consumption for 48h upon administration

23

Wide activity against nematodes killing adult worms in the colon but not the eggs

Pyrantel pamoate

24

Causes SJS

Thiabendazole