Anxiety Flashcards
(25 cards)
Drugs that cause anxiety
Albuterol
Antipsychotics
Bupropion
Caffeine
Decongestants
Illicit drugs
Levothyroxine
Steroids
Stimulants
Theophylline
Non drug treatment for anxiety
Cognitive Behavioral Therapy
St John’s wort
Valerian
Passionflower
Kava
First lines for anxiety
SNRI and SSRI:
Wscitalopram
Fluoxetine
Parxetine
Sertraline
Duloxetine
Venlafaxine XR
When will SNRI and SSRI have full effect
4 weeks → requires slow titrating to minimize anxiety and jitteriness
When does buspirone have effect
2-4 wks
2nd line antianxiety
Bspirone
TCA: Amitriptyline, Nortriptyline
Hydroxyzine
Pregabalin
Gabapentin
What is hydroxyzine
Sedating antihistamine → should not be used long-term
Drug indicated for stage fright
Propranolol
MOA of buspirone
Has an affinity for 5-HT1A and 5-HT2 receptors
CI of buspirone
Avoid MOAI and IV methylene blue → Serotonin syndrome
Why is buspar a good drug
No potential for abuse, tolerance, or physical dependence
MOA of BZD
Enhance GABA (inhibitory neurotransmitter) → CNS depression
Indication for BZD
Acute anxiety (short-term relief), should be limited to 1-2 wks
Sleep
Seizures
Why are BZDs on the BEER list
Increased sedation, fall, confusion, CNS depressants
Paradoxical effect (hyperactivity, aggregation, agitation)
BZDs that are safe in elderly?
Lorazepam
Oxazepam
Temazepam
Alprazolam
Prozac
Clonazepam
Klonopin
Diazepam
Valium
Lorazepam
Ativan
BBW of BZDs
Take with opioids → respiratory depression, sedation
Abuse, misuse, and addiction
Physical dependences → slow taper to prevent withdrawal
CI of BZDs
Severe liver disease
ADR of BZDs
CNS depression, anterograde amnesia, abuse, risks in elderly
CI: pregnancy
Somnolences, dizziness, ataxiaB
BZDs indicated for alcohol withdrawn syndrome
Lorazepam, diazepam, chlodiazepoxide
Antidote for BZD
Flumazenil
