Flashcards in April 10 Deck (9)
What are features of chronic bronchitis?
Thickened bronchial walls
Mucous gland enlargement --increased goblet cells
Squamous cell metaplasia
Cigarette smoking is the leading cause
What is the cause of tetralogy of fallot?
Due to deviation of infundibular septum
--most common cause of early childhood cyanosis
--squatting: increases SVR, decreases right-to-left shunt--improves cyanosis
What inherited disorder is caused by deficient DNA repair enzymes and is characterized by DNA hypersensitivity to ionizing radiation?
Disorder of the inner ear characterized by increased volume and pressure of endolymph due to defective resorption?
Meniere disease --causes damage to vestibular and cochlear components of the inner ear
-Low frequency tinnitus
-Sensorineural hearing loss
What is the 1st line tx for OCD?
--Target is 5-HT
What is the major immune mechanism against Giardia?
CD4+ T helper cells and secretory IgA production---impairs adherence to the small bowel mucosa
How do ACE inhibitors cause an increased Cr shortly after being started?
Blockage of Angiotensin II action on the efferent arteriole causes vasodilation of the arteriole--decreasing GFR and increasing CR.
Angiotensin II normally vasoconstricts the efferent
What NSAID does NOT impair platelet function?
COX-2 selective Celecoxib