Arthritis Classifications and Auto-immunity Flashcards Preview

The Musculoskeletal System > Arthritis Classifications and Auto-immunity > Flashcards

Flashcards in Arthritis Classifications and Auto-immunity Deck (18):
1

Arthritis can be classified into which two main categories?

  1. Inflammatory
  2. Non-inflammatory

2

What are the four types of inflammatory arthritis?

  1. Seropositive
  2. Seronegative
  3. Infectious
  4. Crystal induced

3

What are the five types of seropostive inflammatory arthritis?

  1. Rheumatoid arthritis
  2. Lupus
  3. Scleroderma
  4. Vasculitis
  5. Sjogren's

4

What are the four types of seronegative inflammatory arthritis?

  1. Anklosing spondylitis
  2. Psoriatic arthritis
  3. Reactive arthritis
  4. Inflammatory bowel (enteropathic) arthritis

5

What are seropositive conditions?

Conditions in which there is auto-antibody production 

This is characteritic of many rheumatological conditions

6

Loss of immune regulation (autoimmune condition) is due to which two factors?

  1. Genetic predisposition
  2. Environmental triggers

7

Anti-CCP antibodies are associated with which condition?

Rheumatoid arthritis

8

Anti-nuclear antibodies are associated with which conditions?

  1. SLE
  2. Sjogren's syndrome
  3. Systemic sclerosis
  4. Mixed connective tissue disease (MCTD)
  5. Autoimmune liver disease

9

Anti-double stranded DNA antibody (Anti-dsDNA) is associated with which condition?

SLE

10

Anti-Sm antibody is associated with which condition?

SLE

11

Anti-Ro antibody is associated with which conditions?

  1. Sjogren's
  2. SLE

12

Anti-La antibodies are associated with which condition?

Sjogren's

13

Anti-centromere antibody is associated with which condition?

Systemic sclerosis (limited)

14

Anti-Scl-70 antibody is associated with which condition?

Systemic sclerosis (diffuse)

15

Anti-RNP antibody is associated with which conditions?

  1. SLE
  2. Mixed connective tissue disease

16

Anti-Jo-1 antibody is associated with which condition?

Myositis

17

Anti-phospholipid syndrome is associated with which antibodies?

  1. Anti-cardiolipin antibody
  2. Beta-glycoprotein 2
  3. Lupus anticoagulant

18

Small vessel vasculitis is generally associated with which antibody?

Anti-neutrophil cytoplasmic antibody (ANCA)

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