Asthma for the Clinician Flashcards Preview

Jason's MD2 Core Conditions > Asthma for the Clinician > Flashcards

Flashcards in Asthma for the Clinician Deck (27)
0

pathophysiology of asthma?

mast cell and eosinophil degranulation in response to allergin,

1

what three things describe an asthma airway

bronchoconstriction, oedema, mucous

2

what happens to airways in chronic inflammation from asthma

structural changes, epithelial damage

3

what 3 things is involved in airway remodelling from Asthma?

smooth muscle hyperplasia
goblet cell hyperplasia
thickening of basement membrane

4

is there a genetic predisposition for asthma?

polygenetic

5

what is AHR? meaning?

airway hyperresponsiveness (Not asthma but more likely to develop)

6

Name 9 triggers of asthma?

Allergens
Pollutants (smoke, fumes)
URTIs
Cold dry air
exercise
emotion/anxiety
food
meds
GORD

7

that meds can trigger asthma?

aspirin
betablockers

8

what kind of flow in a wheeze?

turbulent

9

when do you see pulsus paradoxus? 2 times?

asthma
pericarditis

10

how does normal airway air flow?

laminar

11

how are breathsounds and heart sounds during asthma attack?

reduced

12

how to confirm asthma with spirometry?

200ml or 12% improvement with bronchodilator

13

how to confirm asthma with peak expiratory flow?

20% variation day to day

14

what is spirometry is unremarkable for asthma?

bronchoprovocation test

15

5 other causes of wheeze?

bronchitis
obstruction (tumour, foreign body)
COPD exacerbation
vocal cord dysfunction
heat

16

how to tell is wheeze is a vocal cord dysfunction?

expiratory wheeze concentrated in the larynx

17

why would you have inhaled corticosteroids to treat someone's moderate asthma?

prevent airway remodelling and mucous secretion rather than just treating symptoms

18

medications in asthma should follow which principles?

lowest dose to achieve suitable asthma control and minimal side effects

19

what not to forget when treating asthma in adults to be patient focused?

psychosocial factors and education

20

how NOT to give Beta 2 Agonist?

don't give LABA alone

21

when use combo inhalers?

if corticosteroids alone doesn't work LABA/ICS

22

when use leukotriene receptor antagonists?

children, with tablets, not really great for adults

23

side effects of beta agonists and ICS?

palpatations for SABA/LABA
oral thrush for ICS

24

what is ciclesonide used for?

ICS that's less harsh on vocal cord, used for singers with asthma

25

how to ask for adherence?

how often do you renew your script?

26

how to treat severe life threatening asthma attack? 5 things

admit to ICU
oxygen
oral or IV prednisolone
SABA nebulized
supportive breathing
IV magnesium