Breast Disease Flashcards Preview

Jason's MD2 Core Conditions > Breast Disease > Flashcards

Flashcards in Breast Disease Deck (25)
1

Important questions on family history for breast cancer

Male breast cancer
materal vs. paternal
bilateral breast cancer?

2

other cancers that matter?

Prostate: BRCA2
Ovarian: BRCA1
Familial gastric cancer

3

what race/population more at risk of breast cancer?

Eastern Europe Jewish population ashkenazi

4

why is breast cancer less risk with breast tissue?

exposure to estrogen and pregnant makes breast tissue more differentiated, less likely to be become malignant

5

2 physiological conditions that cause more estrogen.

pregnancy
obesity

6

2 conclusions at end of examination

normal
not sure if malignant

7

breast screening ages in Australia?

50-75 mammography every 2 years

8

Investigations for a 37 year old, and found a lump?

Ultrasound
Mammogram

9

likely dx for a young female who finds a lump

Cyst
fibroadenoma
area of fibrocystic changes

10

aspirating a cyst, dangerous when fluid is?

if cyst fluid is bloody

11

types of biopsy?

incisional
excision
FNA
Core
'liquid' (not available yet)

12

breast cancer metastasize most common place first?

bone>>lung>>liver>>brain

13

bone scans for staging for breast cancer?

usually not if they are asymptomatic

14

5 treatments for breast cancer?

biologics
surgery
endocrine therapies (selective estrogen antagonists)
radiotherapy
chemotherapies

15

why mastectomy if someone is BRCA carrier?

risk of a new primary

16

don't want to irradiate if what condition?

scleroderma

17

why won't you irradiate someone?

if they've had radiation before in the area

18

role of axillary surgery?

1.to biopsy it and prognosis
2. guiding management
3. prevent spread (local control)
4. treat spread

19

sentinel node hypthesis

that drainage of a certain area must go through this node

20

more info for breast cancer after excision?

endocrine sensitive?
HER2 amplification
immunohistochemistry

21

if over 35, and planning to have a family? what will be problems?

fertility: hemo, rad, herceptin will affect
Ovum and embryo stored

22

chemo do what to ovaries?

induces menopause

23

if wants preg and still on therapy?

need hiatus in endocrine treatment, usually 5-10 years

24

Best lifestyle things to prevent reoccurrence?

exercise and no smoking

25

When is young age of breast cancer?

under 50
particularly under 40