COPD Flashcards Preview

Jason's MD2 Core Conditions > COPD > Flashcards

Flashcards in COPD Deck (27)
1

S. Typhi vaccine protected against?

S. Typhi, NOT S. paratyphi

2

main cause of COPD?

smoking

3

COPD definition?

group of disorders causing airway inflam, airflow limitation, not reversible

4

4 classic features of COPD?

chest hyperinflation
prolonged expiration
reduced breath sounds
reduced FEV1/FVC

5

COPD inflammation causes 2 kinds of damage:

small airways disease
parenchymal destruction

6

why do you get parenchymal destruction in COPD?

chronic inflamm
macrophages,
proteinase-antiproteinase imbalance
oxidative stress

7

why do you get hypoxia in COPD?

lose alveolar surface area: increased pulmonary vascular pressures

8

how do you get emphysema with COPD?

protease destruction of alveolar wall proteins

9

what is a bullae?

large emphyseamatous cavity in lung, not functional

10

what is alpha-1 antitrypsin do?

mops up elastase in the lung normally

11

how to calculate the FER?

FEV1/FVC

12

FER airflow obstruction cutoff number?

<0.7

13

what lung structure does asthma NOT affect?

lung parenchyma

14

fibrosis in asthma?

nope

15

astham affects which airways?

all of them large and small

16

COPD affects which airways?

peripheral aiways

17

mucus hypersecretion more in COPD or Asthma?

COPD

18

gold classification for stage 1-4 and FEV1% are what?

1: >80%
2: 50-80%
3: 30-50%
4: <30%

19

what is varenicline for?

smoking cessation

20

what is tiotropium?

LAMA

21

when do you use corticosteroids for COPD?

severe FEV1<50% COPD

22

what 2 things not to forget to ask in OSCE?

Pulmonary Rehabilitation
Mood and psychosocial/anxiety

23

2 vaccines you should always get if you have COPD?

Influenza
Pneumococcal

24

O2 and COPD improves what?

mortality, not morbidity

25

how would surgery help in COPD?

remove bullae

26

what is 3 COPD exacerbation anthonisen criteria? how treat if present?

more dyspnoea
more sputum
more discoloured sputum

treat with Antibiotics

27

what is Haldane effect?

O2 displaces CO2 from Hb