Auditory Flashcards

1
Q

Vestibulocochlear nerve is for _____ and ______

A

hearing
equilibrium

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2
Q

What is the bony labyrinth of the inner ear?

A

passageways in petrous temporal bone

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3
Q

What is the membranous labyrinth?

A

connective tissue tubes within bony labyrinth

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4
Q

What is the membranous labyrinth filled with?

A

endolymph (blue fluid), similar to intracellular fluid, high in K+

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5
Q

What is the membranous labyrinth floating in?

A

perilymph (similar to cerebrospinal fluid)

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6
Q

What is the cochlea?

A

organ of hearing

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7
Q

Define scala vestibuli

A

dorsal chamber
filled with perilymph
begins at oval window and spirals to apex

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8
Q

Define scala tympani

A

ventral chamber
filled with perilymph
begins at apex and ends at round window
secondary tympanic membrane

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9
Q

Define scala media (cochlear duct)

A

triangular middle chamber
filled with endolymph (K+ rich)

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10
Q

Stereocilia of hair cells of organ of corti are embedded in the _________

A

tectorial membrane

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11
Q

When the basilar membrane moves up, _____ are pushed into the tectorial membrane

A

hair cells

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12
Q

What is pulled that opens ion channels in the hai cell?

A

tip links

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13
Q

What ion diffuses into the hair cell and depolarizes it?

A

K

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14
Q

What is conductive deafness?

A

conditions interfere with transmission of vibrations to inner ear
- damaged tympanic membrane
- otitis media
- tumors, polyps

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15
Q

What is sensorineural (nerve) deafness?

A

death of hair cells, CN VIII, or any CNS system elements concerned with hearing
- genetic (congenital)
- geriatric (age-related)
- acquired (infections, trauma, loud noises, tumor)

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16
Q

What is the first order neuron for the auditory pathway?

A

cochlear n.

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17
Q

Where is the cochlear nuclei located?

A

medulla

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18
Q

What are 2nd order neurons of the auditory pathway?

A

dorsal nucleus of the trapezoid body (superior olivary nucleus) —> decussate —> DNTB or lateral lemniscus

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19
Q

The caudal colliculus is associated with the ______

A

tectospinal tract

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20
Q

The medial geniculate nucleus is associated with the _______

A

primary auditory cortex (temporal lobe)

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21
Q

The vast majority of signals end up in [ipsilateral/contralateral] auditory cortex

A

contralateral

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22
Q

What is the acoustic startle reflex?

A

reflex turning of head and neck

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23
Q

Trace the acoustic startle reflex pathway.

A

caudal colliculus in midbrain —> rostral colliculus —> to tectospinal tract —> stimulate neck muscles IPSILATERAL to sound

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24
Q

What nerves does the stapedius reflex involve?

A

vestibulocochlear n.
facial n.

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25
Olfaction and gustation receptors are _______
chemoreceptors
26
What is the primary afferent neuron for olfactory receptor cells?
olfactory receptor cell
27
What is a gustatory receptor?
specialized epithelial cell ("sense organ") that transducer chemical signals and then sends electrical signals to the primary afferent neuron
28
What does sniffing accomplish?
bring odorants into olfactory areas
29
Sniffing is under [unidirectional/bidirectional] flow
unidirectional flow localize scents expel air to purge and sniff again
30
The [right/left] nostril is for familiar scents, and the [right/left] nostril is for novel or noxious smells
left right
31
Where do olfactory receptors only line?
olfactory epithelium on ethmoturbinates
32
The rest of the turbinate lining is made up of ______, with no olfactory capacity
respiratory epithelium
33
Olfactory epithelium has neurons exposed to ______
external environment
34
Define olfactory receptor cells
primary afferent neuron (bipolar)
35
________ bind to receptors located on cilia that protrude into the _______
odorant molecules nasal cavity
36
List things in olfactory epithelium
olfactory receptor cells supporting cells basal cells
37
What is one of the only neurons that is a stem cell and CAN replace itself?
basal cells in the olfactory epithelium
38
Where does the odorant bind on the olfactory receptor cell?
G-protein coupled receptor
39
What does the G-protein subunit activate which converts ATP to cAMP?
adenylyl cyclase
40
cAMP opens ___, ___, and _____ channels
Na+ K+ Ca2+
41
The membrane in olfactory transduction is [depolarized/hyperpolarized]
depolarized
42
At the end of olfactory transduction, an action potential is generated in ________
olfactory neurons axon
43
What is the first order neuron for the olfactory path?
through cribriform plate to olfactory bulb
44
What do olfactory bulb interneurons do?
process, filter, enhance transmission of specific odorants
45
What is the 2nd order neuron in the olfactory path? Where does it go?
mitral cell axons project to cerebellum
46
T/F: There is a conscious perception before the thalamus
TRUE
47
Where is the olfactory cortex located?
piriform lobe
48
In the olfactory pathway, transmission through the _____ is not required
thalamus
49
What is the accessory olfactory system?
vomeronasal organ that is connected to the nasal and oral cavity via the nasopalatine ducts
50
______ are introduced to the nasopalatine ducts through inhalation in some species and through liquid/mucus in others
pheromones
51
Vomeronasal organ fibers go to ______ and then to the ________
accessory olfactory bulb olfactory cortex
52
What are the sensory organs for taste?
taste buds
53
Taste buds are found on ______
gustatory papillae
54
Taste buds contain what kinds of cells?
specialized epithelial cells supporting cells basal cells (like olfactory epithelium)
55
What contains chemoreceptors in the taste receptor cells?
microvilli
56
Bitter, sweet, or savory uses what?
G-protein coupled receptor (IP3, Ca2+)
57
What does the signaling cascade for bitter, sweet, and savory open?
transient receptor potential channels (TRP) - receptor cell then depolarized
58
Salty has a lot of ______
Na+
59
Sour has a lot of _____
H+
60
What pathway does salty and sour use for taste transduction?
chemicals bind and directly open inotropic epithelium sodium channels to allow H+ or Na+ to enter - receptor cells is depolarized
61
What are the primary afferents axons of the first order neurons in? (what nerves)
7, 9, 10
62
Where is the second order neuron for the gustatory pathway?
solitary nucleus of the medulla
63
Second order neurons send ______ to third order neurons in the ____ in the gustatory pathway
axon projections thalamus
64
In the gustatory pathway, third order neurons project to the "_______" of the temporal lobe in cerebral cortex
taste cortex seems like this pathway is ipsilateral