Autoimmune Conditions: sjogren's syndrome Flashcards Preview

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Flashcards in Autoimmune Conditions: sjogren's syndrome Deck (14)
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1
Q

How is sjogrens syndrome characterized?

A

dry eyes

dry mouth

2
Q

Sjogren’s can be primary and secondary to what?

A

RA, SLE

3
Q

Dry mouth and dry eyes are a touch of significant morbidity for these patients and can lead to complications such as:

A

dental caries corneal ulceration and chronic oral infections

4
Q

No known cure, but treatment focuses on

A

reducing symptoms of dry eyes and dry mouth

5
Q

What is the primary treatment?

A

artificial drops - Systane, Refresh, Clear Eyes, Liquifilm

6
Q

What is the name of the preservative that might be irritating?

A

benzalkonium chloride

7
Q

What can be used in patients who do not have satisfactory relief from other measure including ductal occlusion

A

cyclosporine eye drops (Restasis) $$$$$$$$

  • must be used properly to avoid infection
8
Q

What drug is approved for the treatment of signs and symptoms of dry eye disease?

A

lifitegrast/ Xiidra

9
Q

This drug has an unusual taste

A

Xiidra

10
Q

What are non-drug treatment options?

A

salivary stimulation - sugar free chewing gum (xylitol or lozenges) and

daily rinses with antimicrobial mouthwash

11
Q

If OTC treatments (Aquoral, Mouth Kote, Biotene Oral Balance)provide sufficient relief, what next?

A

Rx oral muscarinic agonists (pilocarpine or cevimeline) can be used

12
Q

the oral muscarinic agonists are contraindicated in what Patient population?

A

uncontrolled asthma and narrow angle glaucoma

13
Q

Brand: Salagen

A

generic: pilocarpine

14
Q

Brand: Evoxac

A

generic: cevimeline