Autonomic Pharmacology

Question 1

Primary transmitter at cholinergic nerve endings (preganglionic ANS, postganglionic parasympathetic, post- ganglionic sympathetic to thermoregulatory sweat glands, and somatic neuromuscular end plates)

Answer 1

Acetylcholine

Question 2

Sympathomimetic drug that facilitates the release of catecholamines from adrenergic nerve endings

Answer 2

Amphetamine

Question 3

acterial toxin that enzymatically disables release of acetylcholine from cholinergic nerve endings

Answer 3

Botulinum

Question 4

Sympathomimetic drug that impairs reuptake of catecholamine transmitters (norepinephrine, dopamine) by adrenergic nerve endings; it is also a local anesthetic

Answer 4

Cocaine

Question 5

Blocks VAT transporter of Ach

Answer 5

Vesamicol

Question 6

Tyrosine hydroxilase inhibtor

Answer 6

Metyrosine

Question 7

blocks VMAT transporter of Dopamine

Answer 7

Reserpine

Question 8

upregulates NE release

Answer 8

Ephedrine

Amphetamine

Question 9

Blocks NE release

Answer 9

gunethedine

Question 10

Blocks NE reuptake

Answer 10

cocaine

amphetamine

Question 11

Increase vascular smooth muscle contraction, pupillary dilator muscle contraction, intestinal and bladder sphincter muscle contraction

Answer 11

a1

Question 12

DECREASE sympathetic outflow, insulin release, lipolysis, aqueous humor priduction

Answer 12

a2

Question 13

Increase HR, contractility, renin release, lipolysis

Answer 13

B1

Question 14

Vasodilation, bronchoconstriction, Inc lipolysis, inc insulin release,

DEC uterine tone
Cilliary muscle relaxation,
Increase tears

Answer 14

B2

Question 15

CNS, enteric nervous system

Answer 15

M1

Question 16

DEC HR, and contractility of atria

Answer 16

M2

Question 17

Dec exoc gland secretion

Answer 17

M3