Autonomic Pharmacology Flashcards Preview

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Flashcards in Autonomic Pharmacology Deck (17)
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1

Primary transmitter at cholinergic nerve endings (preganglionic ANS, postganglionic parasympathetic, post- ganglionic sympathetic to thermoregulatory sweat glands, and somatic neuromuscular end plates)

Acetylcholine

2

Sympathomimetic drug that facilitates the release of catecholamines from adrenergic nerve endings

Amphetamine

3

acterial toxin that enzymatically disables release of acetylcholine from cholinergic nerve endings

Botulinum

4

Sympathomimetic drug that impairs reuptake of catecholamine transmitters (norepinephrine, dopamine) by adrenergic nerve endings; it is also a local anesthetic

Cocaine

5

Blocks VAT transporter of Ach

Vesamicol

6

Tyrosine hydroxilase inhibtor

Metyrosine

7

blocks VMAT transporter of Dopamine

Reserpine

8

upregulates NE release

Ephedrine
Amphetamine

9

Blocks NE release

gunethedine

10

Blocks NE reuptake

cocaine
amphetamine

11

Increase vascular smooth muscle contraction, pupillary dilator muscle contraction, intestinal and bladder sphincter muscle contraction

a1

12

DECREASE sympathetic outflow, insulin release, lipolysis, aqueous humor priduction

a2

13

Increase HR, contractility, renin release, lipolysis

B1

14

Vasodilation, bronchoconstriction, Inc lipolysis, inc insulin release,

DEC uterine tone
Cilliary muscle relaxation,
Increase tears

B2

15

CNS, enteric nervous system

M1

16

DEC HR, and contractility of atria

M2

17

Dec exoc gland secretion

M3