Blood Pharmacology Flashcards Preview

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Flashcards in Blood Pharmacology Deck (15)
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1

Intrinsic pathway
Antithrombin II
PTT for monitoring

Heparin

2

Heparin AE

Heparin induced thrombocytopenia
Osteoporosis

3

good bioavailability
Factor Xa

LMW Heparin

4

Extrinsic
Vit K dependent

Warfarin

5

How do you monitor warfarin

PROTIME/INR

6

Used for
VHD
DVT
Afib

warfarin

7

Warfarin Side effects

teratogenic
Skin tissue necrosis

8

Treatment for warfarin toxicity

Vit K, FFP

9

Inhibits cylcogenase and thromboxane A2

Aspirin

10

First line for ischemic stroke

Aspirin

11

MC Side effect of aspirin

Gastric irritation due to dec prostaglaindin (gastric mucosa protection)

12

Aspirin AE

REYES' syndrome
fullminant hepatitis

13

inhibits ADP binding to receptor
inhibits glypoprotein GPIIa/IIb
inhibits platelet aggregatio

Clopidogrel

14

inhibits thombin

Dabigatran (pradaxa)

15

Heparin toxicity antidote

Protamine