Cardiovascular Drugs Flashcards Preview

Pharma > Cardiovascular Drugs > Flashcards

Flashcards in Cardiovascular Drugs Deck (67)
Loading flashcards...
1

MOA of Simvastatin

HMG-COA reductase inhibitor

2

Effect of Simvastatin

Lowers T. chol, LDL and Trig
Increases HDL

3

Marker for muscle injury

TotalCK

4

Simvastatin Side effects

Increase LF test
Myositis
Myopathy

5

Liporotein lipase inhibitor; Obesity

Orlistat

6

Orlistat Side effect

Steatorrhea

7

Decreases VLDL
inreases catabolism
decrease hepatic cholesterol synthesis

Nicotinic Acid (Niacin B3)

8

Nicotinic acid (niacin) AE

Facial flushing
Liver toxicity

9

Best drug for TGL control

Fibrates

10

What mimics amphetamine and is used for the treatment of obesity

sibutramine

11

Give 2 antihypertensives that affects the sympathetic nerve terminals

Guanethidine
Reserpine

12

MOA of guanethidine

depletes NE

13

MOA of reserpine

prevent vesicular uptake of NE

14

Reserpine AE

sensonural changes
suicidal ideation
mental depression

15

common side effects of centrally acting antiHPN

sedation, headache

16

HPN commonly used in pregnancy

Methyldopa

17

Methyldopa AE

(+) coombs
lactation
impotence
Drug induced lupus

18

Clonidine AE

rebound HPN
headache

19

3 examples of alpha adrenergic blockers

prazosin
terazosin
doxazosin

20

alpha blockers AE

first dose Othrostatic hypotension

21

"olol" drug classification

Beta blockers

22

Beta blockers adverse effects

Bronchoconstricion, impotence

23

B-blockers are used in caution to patients with what condition?

ASTHMA

24

Part of the vascular system with masimum PVR

arterioles

25

Direct vasodilator used in preeclampsia

Hydralazine

26

Minoxidil side efects

hirsutism
male baldness

27

Direct vasodilator the dilates both the arterioles and venules

Na nitropusside

28

Common drugs used in Malignant HPN

Diazoxide
Na Nitropusside
Nicardipine

29

BP goal for malignant HPN

25% bp reduction

30

MOA of diazoxide

opens K channel